ArticleInternational journal of women's health2026
Impact of Short-Term Estrogen Therapy on Endometrial Polyps Recurrence in Women with Intrauterine Adhesion and Endometrial Polyps: A Retrospective Cohort Study.
Article in International journal of women's health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To investigate whether short-term postoperative estrogen-related therapy is associated with recurrence of intrauterine adhesions (IUA), endometrial polyps (EPs), and pregnancy outcomes in women with concomitant IUA and EPs. Methods: This single-center retrospective cohort study included women (18-45 years) diagnosed with both IUA and EPs who underwent concurrent hysteroscopic transcervical resection of adhesions (TCRA) and polypectomy from January 2019 to June 2024. Patients were grouped by postoperative regimen: (1) estradiol-dydrogesterone sequential therapy (Femoston; estradiol 2 mg/dydrogesterone 10 mg; 2-3 months), (2) combined oral contraceptive (Yaz; ethinylestradiol 0.02 mg/drospirenone 3 mg; 3 months), or (3) no hormonal therapy. Recurrence was confirmed by transvaginal ultrasound and/or hysteroscopy. Results: A total of 166 women were included (sequential therapy, n=47; COC, n=32; no hormone, n=87). Baseline polyp multiplicity differed among groups (P=0.003), with a higher proportion of multiple EPs in the COC group. Postoperative IUD/balloon placement also differed among groups (P=0.012). Overall recurrence rates were 6.6% for IUA and 4.8% for EPs. No statistically significant differences were observed among groups in postoperative menstrual changes, recurrence rates, time to recurrence, or pregnancy outcomes (all P>0.05). Follow-up duration did not differ significantly among groups. Conclusion: In this retrospective cohort, no statistically significant differences were observed among short-term sequential estrogen-progestin therapy, COC use, and no hormonal therapy with respect to IUA recurrence, EP recurrence, or pregnancy outcomes. Short-term estradiol-dydrogesterone therapy was not associated with increased EP recurrence in women with IUA and a single EP. These findings are observational and should be confirmed in prospective studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.