ReviewCureus2026
Knowledge and Attitude Toward Human Papillomavirus (HPV) and Its Vaccination in the Saudi Population: A Systematic Review.
Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human papillomavirus (HPV) vaccination represents an important public health opportunity in Saudi Arabia. This systematic review aimed to evaluate knowledge, attitudes, and uptake regarding the HPV vaccine among various demographic groups in the country. Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, a comprehensive search of databases, including PubMed/MEDLINE, Embase, Web of Science, Scopus, Cochrane Library, and PsycINFO, was conducted from inception through December 2025. The review included studies providing quantitative data on HPV vaccine knowledge, attitudes, beliefs, or uptake. A total of 28 studies published between 2014 and 2024 were analyzed, including studies involving parents, students, and healthcare professionals. Findings revealed a notable prevention paradox: while reported willingness to vaccinate was moderate to high (29.1-87.9%), actual vaccination uptake was consistently low (1-23%). Significant gaps in knowledge were identified, with limited awareness of HPV's association with cervical cancer and optimal vaccination timing. Factors such as higher education and healthcare employment predicted greater acceptance, whereas barriers included safety concerns, insufficient provider engagement, and sociocultural influences. The review concludes that suboptimal HPV vaccine uptake stems largely from systemic and informational gaps. A coordinated national strategy, featuring public education, healthcare provider training, and programmatic interventions such as school-based vaccination, is urgently needed to improve coverage and reduce HPV-related cancer burden.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.