ArticleCureus2026
Healing Patterns of Periodontal Intrabony Defects Following Allograft and Alloplast Therapy: A Prospective Randomized Clinical Trial.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
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Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVertical periodontal bone defects pose a significant challenge in regenerative therapy. This study compared the clinical and radiographic outcomes of freeze-dried bone allograft (FDBA) and biphasic calcium phosphate (adbone®BCP) in patients with chronic periodontitis.
methodsTwenty systemically healthy patients were randomized into two groups to receive either FDBA or AdboneBCP following open flap debridement. Clinical parameters, pocket probing depth (PPD) and relative attachment level (RAL), and radiographic bone fill (RBF) were assessed at baseline, three months, and six months postoperatively.
resultsBoth graft materials led to significant improvements over six months. Mean PPD reduction was 4.2 mm with FDBA and 3.9 mm with AdboneBCP; mean RAL gain was 3.8 mm and 3.5 mm, respectively. Radiographic bone fill averaged 62% for FDBA and 58% for AdboneBCP. Differences between groups were not statistically significant. No adverse events were reported.
conclusionsAdboneBCP is a safe, effective, and predictable synthetic alternative to FDBA for regenerating vertical periodontal defects. Its comparable clinical and radiographic outcomes support its use in scenarios where allograft availability is limited.
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