Evidence map›Paper›PMID 41835703›Full record

ArticleCureus2026

Surgical Resection of Abdominal Solid Organ Tumors With Inferior Vena Cava Extension: A Single-Center Experience With Long-Term Follow-Up.

Nikoleta Stanitsa, Filippos-Paschalis Rorris, Konstantinos Antonopoulos, Emmanouil Tempelis, Aikaterini Dedeilia, Ilias Samiotis, Anastasios Athanasopoulos, Eleni Papagianni, Nikolaos Schizas, Panagiotis Dedeilias

Abstract read
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nikoleta StanitsaCardiothoracic Surgery, Evangelismos General Hospital, Athens, GRC.
Filippos-Paschalis RorrisCardiac Surgery, Onassis Hospital, Athens, GRC.
Konstantinos AntonopoulosVascular Surgery, "Attikon" University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, GRC.
Emmanouil TempelisCardiac Surgery, Evangelismos General Hospital, Athens, GRC.
Aikaterini DedeiliaSurgery, Boston Medical Center, Boston, USA.
Ilias SamiotisCardiothoracic Surgery, Evangelismos General Hospital, Athens, GRC.
Anastasios AthanasopoulosCardiothoracic Surgery, Evangelismos General Hospital, Athens, GRC.
Eleni PapagianniPathology, Evangelismos General Hospital, Athens, GRC.
Nikolaos SchizasCardiac Surgery, "Attikon" University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, GRC.
Panagiotis DedeiliasCardiothoracic Surgery, Evangelismos General Hospital, Athens, GRC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAbdominal solid organ malignancies, particularly renal and adrenal tumors, may extend into the inferior vena cava (IVC) as tumor thrombus and, in rare cases, reach the right atrium. Surgical management is technically demanding and associated with significant perioperative risk. This study evaluates perioperative outcomes and long-term survival after radical resection of abdominal tumors with IVC extension using cardiopulmonary bypass (CPB). MATERIALS AND

methodsA prospectively maintained dataset was retrospectively analyzed for adult patients who underwent surgical management of abdominal solid organ tumors with IVC extension between June 2002 and September 2023 at a tertiary referral center. Procedures were performed by a multidisciplinary team. CPB was used in all cases. The extent of venous involvement was categorized using the Mayo Clinic classification system. The primary outcome was long-term survival, and secondary outcomes included perioperative complications and in-hospital mortality.

resultsThirty-nine patients underwent resection (mean age 61 ± 11.3 years; 74.3% male). Tumors originated most commonly from the kidney (87.1%), followed by the adrenal gland (10.3%), with one case of primary IVC intimal sarcoma. Clear cell RCC was the predominant histological subtype. Mean operative duration was 390 minutes; mean CPB time was 145 minutes; mean ischemia time was 55 minutes; and mean hypothermic circulatory arrest (HCA) time was 33 minutes. In-hospital mortality was 10.3%, including two intraoperative deaths. Mean follow-up was 4.8 ± 3.5 years. Estimated overall survival at 1, 5, and 10 years was 87.1%, 64.1%, and 46.1%, respectively.

conclusionsRadical resection of abdominal solid organ tumors with IVC extension using CPB is feasible and can provide acceptable long-term survival despite substantial perioperative risk. A multidisciplinary approach is essential to optimize outcomes in these complex cases.

Indexed as

adrenocortical carcinomacardiopulmonary bypasshypothermic circulatory arrestinferior vena cavalong-term survivalradical resectionrenal cell carcinomathrombectomytransesophageal echocardiographytumor thrombus

Identifiers

PMID41835703
PMCPMC12981606

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.