ReviewCureus2026
Whole-Food Dietary Interventions in Crohn's Disease: A Literature Review.
Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This narrative review examines advances in diet-based therapy for Crohn's disease with a focus on emerging whole-food interventions that have gained attention in the past five years. The aim is to evaluate the current evidence for the Crohn's disease exclusion diet, specific carbohydrate diet, Mediterranean diet, and newer approaches such as CD-TREAT (Crohn's disease treatment with eating diet), low-FODMAP (fermentable oligosaccharides, disaccharides, monosaccharides and polyols) strategies, and plant-based regimens. Drawing on recent randomised controlled trials and mechanistic studies, this review explores how these diets influence clinical outcomes, gut microbiota composition, and mucosal integrity, while identifying limitations, controversies, and gaps in knowledge. In addition to summarising the latest findings, we offer a critical perspective on the potential for personalised nutrition, the integration of diet with pharmacologic therapy, and the need for long-term maintenance studies. The scope is limited to mild-to-moderate Crohn's disease, reflecting the clinical scenarios where dietary interventions are most often applied. This review emphasises the potential for diet to function as a structured therapeutic intervention aligned with patient preferences, provided it is implemented within multidisciplinary care models to ensure efficacy, safety, and sustainability.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.