Evidence map›Paper›PMID 41835659›Full record

ReviewCureus2026

Current Perspectives on the Contralateral Patent Processus Vaginalis: What About the Other Side?

Dimitrios Godosis, Vasileios Mouravas, Paschalis Theotokis, Sofia Gargani, Dimitrios Sfoungaris, Maria Eleni Manthou, Soultana Meditskou, Ioannis Spyridakis

Abstract readReview
In one paragraph

Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dimitrios GodosisDepartment of Pediatric Surgery, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, GRC.
Vasileios MouravasFirst Department of Pediatric Surgery, School of Medicine, Faculty of Health Sciences, General Hospital of Athens "G. Gennimatas", Aristotle University of Thessaloniki, Thessaloniki, GRC.
Paschalis TheotokisLaboratory of Histology and Embryology, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, GRC.
Sofia GarganiLaboratory of Histology and Embryology, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, GRC.
Dimitrios SfoungarisFirst Department of Pediatric Surgery, General Hospital of Athens "G. Gennimatas", Aristotle University of Thessaloniki, Thessaloniki, GRC.
Maria Eleni ManthouLaboratory of Histology and Embryology, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, GRC.
Soultana MeditskouLaboratory of Histology and Embryology, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, GRC.
Ioannis SpyridakisSecond Department of Pediatric Surgery, School of Medicine, Faculty of Health Sciences, Papageorgiou General Hospital, Aristotle University of Thessaloniki, Thessaloniki, GRC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inguinal hernia (IH) repair is frequently performed in pediatric surgery, and the condition appears more often in children born prematurely. A key clinical concern is the possibility of developing a metachronous contralateral inguinal hernia (MCIH). This review discusses potential mechanisms involved in pediatric IH formation, with particular focus on how smooth muscle differentiation and fibrotic remodeling may contribute to incomplete closure of the processus vaginalis (PV). It also considers how evolving diagnostic approaches and surgical techniques have shaped contemporary management. In addition, histopathological evaluation may provide further understanding of PV architecture, support more tailored operative decision-making, and help limit the need for subsequent procedures. Overall, the review emphasizes the importance of investigating the histological and ultrastructural features of IHs and hydroceles, and suggests that variations in smooth muscle differentiation and myofibroblast-related changes within the PV may be linked to persistence of patency and susceptibility to herniation.

Indexed as

contralateral patent processus vaginalishistological characteristicslaparoscopic surgerymetachronous contralateral inguinal herniapediatric inguinal hernia

Identifiers

PMID41835659
PMCPMC12988450

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.