Evidence map›Paper›PMID 41835602›Full record

ArticleACS omega2026

Catalyst-Free Gas-Phase Synthesis of Pyrones via Thermally Induced Aldol Condensation of Acetoacetate Derivatives Using GC-MS.

Fernando Garcia, Barnabas Otoo, Isaac Agyekum

Abstract read
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Fernando GarciaUniversity of North Georgia, Department of Chemistry and Biochemistry, Gainesville Campus, 3820 Mundy Mill Rd, Oakwood, Georgia 30566, United States.
Barnabas OtooDepartment of Chemistry and Biochemistry, Bridgewater College, Bridgewater, Virginia 22812, United States.ORCID https://orcid.org/0000-0002-9915-0732
Isaac AgyekumUniversity of North Georgia, Department of Chemistry and Biochemistry, Gainesville Campus, 3820 Mundy Mill Rd, Oakwood, Georgia 30566, United States.ORCID https://orcid.org/0000-0001-6588-6090

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Traditional pyrone syntheses typically require catalysts, solvents, or high pressures, limiting their sustainability. Here, we report the first catalyst-free, solvent-free gas-phase synthesis of substituted pyrones using gas chromatography-mass spectrometry (GC-MS) as both a reaction platform and analytical tool. Direct injection of methyl, ethyl, propyl, isopropyl, and

Identifiers

PMID41835602
PMCPMC12980194

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.