ArticleACS omega2026
Analysis of Intracellular Fatty Acid Metabolism during Doxorubicin-Induced Senescence of MCF7 Cells Using Raman Imaging.
Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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Abstract
Cellular senescence, a stable growth-arrested state induced by stress or chemotherapeutic agents, is accompanied by metabolic remodeling that supports the senescence-associated secretory phenotype (SASP). Among these pathways, lipid and arachidonic acid (AA) metabolism play central roles in maintaining and propagating the senescent state. Here, we used hyperspectral confocal Raman microscopy to visualize biochemical remodeling in MCF7 human breast adenocarcinoma cells undergoing doxorubicin-induced senescence. Raman spectral analysis and principal component decomposition revealed time-dependent alterations in lipid-associated vibrational modes, particularly CH
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