Evidence map›Paper›PMID 41835462›Full record

ReviewFrontiers in cardiovascular medicine2026

A systematic review and meta-analysis of the efficacy of addition and reduction of Shixiao powder in the treatment of coronary heart disease.

Siyuan Chen, Hui Shen, Yingying Su, Cihang Zhou, Yaping Li

Abstract readReview
In one paragraph

Review in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Siyuan ChenTongde Hospital of Zhejiang Province Affiliated to Zhejiang Chinese Medical University (College of Integrated Traditional Chinese and Western Medicine Clinical Medicine), Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Hui ShenTongde Hospital of Zhejiang Province Affiliated to Zhejiang Chinese Medical University (College of Integrated Traditional Chinese and Western Medicine Clinical Medicine), Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Yingying SuTongde Hospital of Zhejiang Province Affiliated to Zhejiang Chinese Medical University (College of Integrated Traditional Chinese and Western Medicine Clinical Medicine), Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Cihang ZhouTongde Hospital of Zhejiang Province Affiliated to Zhejiang Chinese Medical University (College of Integrated Traditional Chinese and Western Medicine Clinical Medicine), Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Yaping LiDepartment of Outpatient Office, Tongde Hospital Affiliated to Zhejiang Chinese Medical University (Tongde Hospital of Zhejiang Province), Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To evaluate the effectiveness and safety of combining Shixiao Powder with Western medicine for treating coronary heart disease-induced angina. Methods: The databases CNKI, VIP, Wanfang, SinoMed, PubMed, Embase, Web of Science, and Cochrane were searched until March 19th, 2024 for randomized controlled studies on the treatment of angina pectoris in coronary heart disease using Shixiao Powder combined with Western medicine. Quality assessment was conducted using the Cochrane Collaboration's tool. Heterogeneity was tested using the Chi-squared-based Q statistic test and I2 statistic. Results: The study included a total of 15 articles, with 1204 patients in the cohort, divided into 625 cases in the observation group and 579 cases in the control group. Compared to Western medicine alone, the combination of Shixiao powder and Western medicine significantly improved the effective rate in treating angina pectoris of coronary heart disease [RR = 1.25, 95%Cl (1.18-1.32), Conclusion: The current evidence supports that combining Shixiao Powder with Western medicine effectively and safely treats angina pectoris associated with coronary heart disease. Systematic Review Registration: https://www.crd.york.ac.uk/PROSPERO/recorddashboard, PROSPERO CRD42024537794.

Indexed as

angina dectoriscoronary heart diseasecurative effectmeta-analysisShixiao powder

Identifiers

PMID41835462
PMCPMC12982363

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.