ReviewRSC chemical biology2026
Illuminating microtubule functions with small molecules: past, present and future of fluorescent tubulin-binding probes.
Review in RSC chemical biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Towards a systems-level view of the microtubule cytoskeleton and its functions in physiology and disease.Nature reviews. Molecular cell biology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Developing tools for the real-time visualization of tubulin, microtubules, and their dynamics is essential for studying key cellular processes such as cell division, migration, and differentiation. In this context, fluorescent small-molecule probes that bind to distinct and specific sites on microtubules have significantly advanced our understanding of tubulin dynamics and functions. In addition, fluorescent probes targeting tubulin have enabled the development of high-throughput screening assays to identify novel anti-tubulin compounds. In this review, we present a comprehensive overview of currently available fluorescent molecules that bind to tubulin, detailing their chemical structures, binding sites, development strategies and relevance to the study of microtubule functions. We also explore future directions in this field and highlight key fluorescent probes that are still lacking. Developing these tools would enable the investigation of tubulin's diverse cellular roles in even greater depth and support the advancement of tubulin-targeted therapeutics.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.