Evidence map›Paper›PMID 41835157›Full record

ArticleFrontiers in chemistry2026

Plant metabolomics reveals changes in the composition of

Quan Rao, Xiao-Hua Fu, Cong-En Zhang, Guang-Chao Ma, Xiao-Hong Yu, Hao Wu, Zhi-Jie Ma

Erratum issuedAbstract read
In one paragraph

Article in Frontiers in chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Quan RaoDepartment of General Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Xiao-Hua FuBeijing Friendship Hospital, Capital Medical University, Beijing, China.
Cong-En ZhangBeijing Friendship Hospital, Capital Medical University, Beijing, China.
Guang-Chao MaBeijing Friendship Hospital, Capital Medical University, Beijing, China.
Xiao-Hong YuBeijing Friendship Hospital, Capital Medical University, Beijing, China.
Hao WuBeijing Friendship Hospital, Capital Medical University, Beijing, China.
Zhi-Jie MaBeijing Friendship Hospital, Capital Medical University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methods: Here, we hypothesized that liquorice processing affects the components of TwHF. And LC-IT-TOF/MS together with plant metabolomics was applied to analyse the chemical composition of raw TwHF (Raw), TwHF combined with liquorice (Com), and TwHF processed by liquorice (Pro). Results: As a result, three differential compounds in TwHF, including triptolide, celastrol and wilforlide A, were tentatively identified. At the same time, we found that there were nine differential compounds from liquorice, including isoliquiritin, uralenin, coumestrol, liquiritigenin, schaftoside, glycyrrhizic acid, glyyunnanprosapogenin D, uralsaponin B and isolicoflavonol. Conclusion: These results will provide a basis for the scientific and rational use of TwHF processed by liquorice in the clinic.

Indexed as

compositional changesliquoricemetabolomicsprocessedtripterygium wilfordii

Identifiers

PMID41835157
PMCPMC12979392

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.