ArticleRSC advances2026
Temperature-triggered microfluidic fabrication of monodisperse organic particles
Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
6 authors.
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Abstract
We report a microfluidic strategy for fabricating monodisperse organic particles by exploiting temperature-controlled miscibility in mixed solvents exhibiting lower critical solution temperature (LCST) behavior. In a water-diethylene glycol monohexyl ether (C6E2) system, phase separation at elevated temperatures enables controlled generation of monodisperse droplets, which subsequently reprecipitate into particles upon cooling to the miscible state. As a result, poly(vinyl alcohol) microparticles with a coefficient of variation below 9% were successfully obtained. This LCST-driven microfluidic approach offers a general platform for producing highly uniform particles from both polymeric and low-molecular-weight organic compounds.
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Registered trials
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