Evidence map›Paper›PMID 41835046›Full record

ArticleAdvanced pharmaceutical bulletin2025

The Phenomenon of Antimicrobial Resistance in Southern Italy: An Overview of the Current Situation.

Stefano Ruga, Raffaele Petti, Mara Masullo, Fabio Castagna, Roberto Bava, Michelangelo Armenise, Elisabetta Labbate, Carmen Lombardi, Antonio Giordano, Massimiliano Quintiliani and 4 more

Abstract read
In one paragraph

Article in Advanced pharmaceutical bulletin, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Stefano RugaDepartment of Health Sciences, University of Catanzaro Magna Græcia, 88100 Catanzaro, Italy.ORCID https://orcid.org/0009-0008-0401-4027
Raffaele PettiLocal Health Authority, ASL, 71121 Foggia, Italy.
Mara MasulloLocal Health Authority, ASL, 71121 Foggia, Italy.
Fabio CastagnaDepartment of Health Sciences, University of Catanzaro Magna Græcia, 88100 Catanzaro, Italy.
Roberto BavaDepartment of Health Sciences, University of Catanzaro Magna Græcia, 88100 Catanzaro, Italy.
Michelangelo ArmeniseLocal Health Authority, ASL, 71121 Foggia, Italy.
Elisabetta LabbateUniversity of Bari Aldo Moro, 70100, Bari, Italy.
Carmen LombardiUniversity Cattolica of Rome, 00168, Roma, Italy.
Antonio GiordanoSbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, Department of Biology, College of Science and Technology, Temple University, Philadelphia, U.S.A.
Massimiliano QuintilianiSbarro Health Research Organization ETS, 10060, Candiolo (TO), Italy.
Luigi AlfanoDepartment of Breast and Thoracic Oncology, Istituto Nazionale Tumori, IRCSS-G Pascale, 80131, Napoli, Italy.
Emilia LangellaDepartment of Agricultural, Forestry, Food and Environmental Sciences, Università degli Studi della Basilicata Campus di Macchia Romana Via dell'Ateneo Lucano, 10 - 85100 Potenza, Italy.ORCID https://orcid.org/0000-0001-6628-2459
Giovanna LiguoriLocal Health Authority, ASL, 71121 Foggia, Italy.ORCID https://orcid.org/0000-0002-3031-345X
Renato LombardiLocal Health Authority of Foggia, Via Monte Grappa 25, 71121, Foggia, Italy.ORCID https://orcid.org/0009-0005-7759-2141

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Antimicrobial resistance (AMR) is an escalating global health challenge with region-specific implications. This study investigated AMR prevalence in Southern Italy, with particular attention to demographic variables such as gender and age. Methods: A retrospective analysis of antibiograms from 146 patients (68 males and 78 females, aged 36-101 years) collected between 2022 and 2023 was conducted. Given the retrospective design and reliance on routinely collected clinical data from a local hospital microbiology laboratory, molecular analyses were not feasible, as isolates were processed solely for diagnostic purposes and not preserved. Results: The most frequently isolated pathogens were Conclusion: Despite the absence of molecular data, phenotypic surveillance through antibiograms remains a critical tool for monitoring AMR trends in underrepresented regions. Incorporating gender-specific differences into clinical practice may improve therapeutic efficacy and stewardship strategies. These findings provide a foundation for future molecular and epidemiological investigations.

Indexed as

Antimicrobial resistanceDemographicsPublic healthSouthern Italy

Identifiers

PMID41835046
PMCPMC12980278

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.