Evidence map›Paper›PMID 41835015›Full record

ArticleBMJ neurology open2026

United Kingdom Young Stroke Study (UKYSS): study protocol for an ambispective observational study.

Phillip Wilford Ferdinand, Ram Bajpai, Mohammed Shoaib, Holly Maguire, Balamrit Sokhal, Shadman Ahmed, Josh Goraya, Christian Mallen, Christine Roffe

Abstract read
In one paragraph

Article in BMJ neurology open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Phillip Wilford FerdinandNeurosciences, Royal Stoke University Hospital, Stoke-on-Trent, England, UK.ORCID https://orcid.org/0000-0002-8715-2917
Ram BajpaiSchool of Medicine, Keele University, Newcastle-under-Lyme, England, UK.
Mohammed ShoaibNeurosciences, Royal Stoke University Hospital, Stoke-on-Trent, England, UK.
Holly MaguireNeurosciences, Royal Stoke University Hospital, Stoke-on-Trent, England, UK.
Balamrit SokhalNeurosciences, Royal Stoke University Hospital, Stoke-on-Trent, England, UK.
Shadman AhmedNeurosciences, Royal Stoke University Hospital, Stoke-on-Trent, England, UK.
Josh GorayaSchool of Medicine, Keele University, Newcastle-under-Lyme, England, UK.
Christian MallenSchool of Medicine, Keele University, Newcastle-under-Lyme, England, UK.
Christine RoffeSchool of Medicine, Keele University, Newcastle-under-Lyme, England, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: 10%-15% of strokes occur between 18 and 50 years old. Young stroke incidence in the UK is increasing with high risk factor burden and varied aetiology. Long-term functional and psychological sequelae are highly prevalent. This study will provide representative information on UK young strokes and develop a prognostic tool guiding primary and secondary prevention. Methods and analysis: The United Kingdom Young Stroke Study (UKYSS) is an ambispective observational study of young adults aged 18-49 years with a first ever ischaemic or haemorrhagic stroke. Young strokes between 1 January 2013 and 31 December 2020 will be identified from UK stroke centres and screened for eligibility. Data will be collected on demographics, risk factors, clinical presentation, investigation, imaging, diagnosis and discharge status at baseline and survival, vascular events, epilepsy and malignancy. Patients will complete a life after stroke questionnaire to obtain current information on a variety of functional domains.Descriptive analysis will use χ Ethics and dissemination: UKYSS has regulatory and ethical approval. Data will be anonymised and housed securely. Data management and confidentiality will be compliant with national regulations. Results will be submitted to peer-reviewed conferences and journals and disseminated to participants, patient organisations and local media and government organisations. Trial registration number: ISRCTN11029266.

Indexed as

STROKE

Identifiers

PMID41835015
PMCPMC12983979

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.