ArticleEuropean heart journal. Imaging methods and practice2026
Ultrafast power Doppler imaging for RV myocardial perfusion assessment: histopathologic correlation and
Article in European heart journal. Imaging methods and practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Aims: Myocardial vascular remodeling is a key feature in various diseases associated with right ventricular (RV) pressure overload but its non-invasive assessment remains challenging. The new technique attenuation-compensated fractional moving blood volume (acFMBV) based on ultrafast power Doppler (UPD) was developed for myocardial blood volume quantification, linked to RV remodeling and capillary density, but not validated Objectives: To quantify RV myocardial blood volume across the cardiac cycle using UPD in rodent models, with histopathological validation, and assess its feasibility in human patients. Methods and results: Twelve rats (sex ratio 1/1) were randomized to pulmonary artery banding (PAB) ( Conclusion: In this pilot study, UPD-based acFMBV correlates with histological capillary density, supporting its potential as a reliable, non-invasive tool for quantifying RV myocardial blood volume in clinical settings. These observations will need to be confirmed in studies with larger sample sizes. Condensed abstract: Myocardial vascular remodeling in right ventricle (RV) pressure overload is difficult to assess non-invasively. This study validated attenuation-compensated fractional moving blood volume (acFMBV) using ultrafast power Doppler (UPD) to quantify RV myocardial blood volume. Twelve rats underwent pulmonary artery banding (PAB) or sham surgery, with acFMBV measured and correlated with capillary density. PAB rats had lower mid-diastolic acFMBV and capillary density (
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