Evidence map›Paper›PMID 41834810›Full record

ArticleArchives of rehabilitation research and clinical translation2026

Manual Dexterity in Patients with Disorder of Consciousness.

Lingxiu Sun, Anqi Wang, Ziqiang Yang, Jie Huang, Meiqi Li, Yan Chen, Nantu Hu, Lijuan Cheng, Xiaochen Liu, Feng Chen and 5 more

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In one paragraph

Article in Archives of rehabilitation research and clinical translation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

15 authors.

Lingxiu SunInternational Vegetative State and Consciousness Science Institute, School of Basic Medical Sciences, Hangzhou Normal University, Hangzhou, China.
Anqi WangInternational Vegetative State and Consciousness Science Institute, School of Basic Medical Sciences, Hangzhou Normal University, Hangzhou, China.
Ziqiang YangRehabilitation Department II, Zhejiang Rehabilitation Hospital, Hangzhou, China.
Jie HuangSchool of Clinical Medicine and The Affiliated Hospital, Hangzhou Normal University, Hangzhou, China.
Meiqi LiInternational Vegetative State and Consciousness Science Institute, School of Basic Medical Sciences, Hangzhou Normal University, Hangzhou, China.
Yan ChenInternational Vegetative State and Consciousness Science Institute, School of Basic Medical Sciences, Hangzhou Normal University, Hangzhou, China.
Nantu HuInternational Vegetative State and Consciousness Science Institute, School of Basic Medical Sciences, Hangzhou Normal University, Hangzhou, China.
Lijuan ChengSchool of Basic Medicine, Hangzhou Normal University, Hangzhou, China.
Xiaochen LiuDepartment of Rehabilitation, Bule Cross Hospital, Affiliated Hospital of Tongji University, Shanghai, China.
Feng ChenSchool of Nursing, Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
Yufei XueInternational Vegetative State and Consciousness Science Institute, School of Basic Medical Sciences, Hangzhou Normal University, Hangzhou, China.
Aurore ThibautGIGA-Consciousness Coma Science Group, Neurology Department, University Hospital of Liege and University of Liege, Liege, Belgium.
Steven LaureysGIGA-Consciousness Coma Science Group, Neurology Department, University Hospital of Liege and University of Liege, Liege, Belgium.
Siyu DaiInternational Vegetative State and Consciousness Science Institute, School of Basic Medical Sciences, Hangzhou Normal University, Hangzhou, China.
Haibo DiInternational Vegetative State and Consciousness Science Institute, School of Basic Medical Sciences, Hangzhou Normal University, Hangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To examine hand motor features in individuals diagnosed with disorder of consciousness (DoC) after severe brain injury, and to investigate the relationship between manual dexterity and levels of consciousness. Design: Cross-sectional study. Setting: Rehabilitation hospital. Participants: Sixty patients with DoC (44 men and 16 women), with a mean age of 55.03±15.28 years and a mean postinjury duration of 10.68±7.98 months. Interventions: Not applicable (no interventions were administered). Main Outcome Measures: Manual dexterity (Brunnstrom Recovery Stage [BRS]), spasticity (Modified Ashworth Scale), pain (Nociception Coma Scale-Revised), and consciousness (Coma Recovery Scale-Revised) were assessed. Descriptive, nonparametric, and multivariate analyses were performed. Results: Evaluation of the best-functioning hands in the 60 patients with DoC showed that 60% (n=36) had low dexterity (BRS<4), and edema was revealed in 28.3% (17/60) of these hands. Compared with patients in minimally conscious state (MCS), those in unresponsive wakefulness syndrome (UWS) had significantly lower manual dexterity (96.2% vs 32.4%) and a higher prevalence of hand edema (42.3% vs 17.6%). BRS scores were significantly higher for hands than for arms ( Conclusions: A considerable proportion of patients with DoC experience severe hand complications, which can negatively impact their clinical diagnosis and quality of life. The BRS is effective in detecting subtle hand motor responses that may reflect residual consciousness in DoC. The observed association between manual dexterity and consciousness suggests that hand motor control may engage neural circuits involved in consciousness processing.

Indexed as

ComplicationsDisorder of consciousnessManual dexterityRehabilitationUpper limb motor

Identifiers

PMID41834810
PMCPMC12988549

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.