ArticleArchives of rehabilitation research and clinical translation2026
Impact of Pneumonia on Rehabilitation Outcomes: A Large Observational Study.
Article in Archives of rehabilitation research and clinical translation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To evaluate the effect of poststroke pneumonia on rehabilitation outcomes in patients with acute stroke. Design: A prospective observational cohort study. Setting: Rehabilitation services for patients with stroke across 3 hospitals in a low and middle-income country. Participants: A total of 922 patients with stroke (N=922) were enrolled (median age: 67y; 63.7% men) and classified into poststroke pneumonia (PSP; n=296) and nonpneumonia (PSNP; n=626) groups. The patients with PSP were further divided into 2 subgroups based on onset timing including stroke-associated pneumonia (SAP; n=157), defined as diagnosis within 7 days of stroke onset, and hospital-acquired pneumonia (HAP; n=139), defined as pneumonia diagnosed after 7 days. Interventions: Not applicable. Main Outcome Measures: Primary outcome analysis focused on functional outcomes (modified Rankin Scale [mRS]), hospital length of stay (LOS), and mortality were assessed at discharge, 3 months, and 6 months after stroke. Secondary analysis explored predictors of functional outcomes. Results: Patients with PSP demonstrated significantly poorer functional outcomes, with higher mRS scores (≥3) at discharge, 3 months, and 6 months ( Conclusions: Poststroke pneumonia worsens rehabilitation outcomes, prolongs LOS, and increases mortality. Early pneumonia prevention and multidisciplinary integrated rehabilitation, aligned with World Health Organization (WHO) standards, are essential to improve stroke recovery and reduce complications in low- and middle-income countries.
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