Evidence map›Paper›PMID 41834583›Full record

ArticleActa crystallographica. Section F, Structural biology communications2026

X-ray analysis of complexes of carbonic anhydrase II with 1,3-oxazole-containing sulfonamide derivatives elucidates the structural basis for their exceptionally high inhibitory potency.

M Y Stoliarskaia, S S Borisevich, E O Myaskov, A A Shetnev, M K Korsakov, O S Nikonov

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta crystallographica. Section F, Structural biology communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

M Y StoliarskaiaInstitute of Protein Research, Institutskaya 4, Pushchino, Moscow Region, Russian Federation.ORCID 0009-0008-6467-6321
S S BorisevichInstitute of Intellectual Cybernetic Systems, National Research Nuclear University, Moscow Engineering Physics Institute, Moscow, Russian Federation.
E O MyaskovMedicinal Chemistry Center, Togliatti State University, Tolyatti, Russian Federation.
A A ShetnevMoscow Center for Advanced Studies, Moscow, Russian Federation.
M K KorsakovYaroslavl State Pedagogical University named after K. D. Ushinsky, Yaroslavl, Russian Federation.
O S NikonovInstitute of Protein Research, Institutskaya 4, Pushchino, Moscow Region, Russian Federation.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carbonic anhydrase II (CA2) is a zinc metalloenzyme that catalyzes the reversible hydration of CO

Indexed as

Carbonic Anhydrase IICarbonic Anhydrase InhibitorsSulfonamidesAmino Acid SequenceAnimalsCatalytic DomainCattleCrystallography, X-RayHumansLigandsModels, MolecularProtein BindingCarbonic Anhydrase IICarbonic Anhydrase InhibitorsLigandsSulfonamidescarbonic anhydrase IIstructure–activity relationshipsulfonamide inhibitorsX-ray crystallography

Identifiers

PMID41834583
PMCPMC13041629

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.