Evidence map›Paper›PMID 41833810›Full record

Observational studyChest2026

Diagnostic Yield of CT Imaging and Point-of-Care Ultrasound After In-Hospital Cardiac Arrest.

Luke Andrea, Jack Galfund, Lewis A Eisen, Patrick J Coppler, Sarahgrace Lees-Vorhes, Ari Moskowitz

Abstract readObservational StudyMulticenter Study
In one paragraph

Observational study in Chest, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Luke AndreaBronx Center for Critical Care Outcomes and Resuscitation Research, Department of Internal Medicine, Montefiore Medical Center, Bronx, NY. Electronic address: landrea@montefiore.org.
Jack GalfundBronx Center for Critical Care Outcomes and Resuscitation Research, Department of Internal Medicine, Montefiore Medical Center, Bronx, NY.
Lewis A EisenBronx Center for Critical Care Outcomes and Resuscitation Research, Department of Internal Medicine, Montefiore Medical Center, Bronx, NY.
Patrick J CopplerDepartment of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA.
Sarahgrace Lees-VorhesDepartment of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA.
Ari MoskowitzBronx Center for Critical Care Outcomes and Resuscitation Research, Department of Internal Medicine, Montefiore Medical Center, Bronx, NY.

Funding

NRSA Training CoreTL1TR001858 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI RADOMSKI, THOMAS, RUBIO, DORIS M · 2016 to 2025
$11.1M
Hospital Airway Resuscitation TrialR33HL162980 · NHLBI · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI Ari Moskowitz · 2023 to 2026
$3.3M
CTSA K12 Program at Einstein-MontefioreK12TR004411 · NCATS · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI Deepa Rastogi · 2023 to 2026
$3.0M
NCATS NIH HHS K12 TR004411NCATS NIH HHS TL1 TR001858NHLBI NIH HHS R33 HL162980
6 · The paper itself

Abstract

backgroundCT imaging and point-of-care ultrasound (POCUS) have demonstrated usefulness after out-of-hospital cardiac arrest (OHCA), but their diagnostic yield and impact after in-hospital cardiac arrest (IHCA) are unclear. RESEARCH QUESTION: Will CT and POCUS imaging identify acute pathologic features that change postarrest management after IHCA? STUDY DESIGN AND

methodsThis retrospective observational study at 4 hospitals included adults with IHCA who achieved return of spontaneous circulation (ROSC). Patients with OHCA, nonindex arrest, or do-not-resuscitate orders were excluded. CT and POCUS imaging performed within 48 hours of ROSC were reviewed for new findings and management changes. Additional exclusions for CT imaging analysis included death within 24 hours of ROSC.

resultsA total of 345 patients met inclusion criteria. The CT imaging cohort comprised 235 patients (68.1%), and 112 patients (47.7%) underwent CT imaging within 48 hours of ROSC. Head CT imaging was most common (89.3%), followed by CT imaging of the chest (57.1%), abdomen and pelvis (43.8%), and other regions (10.7%). CT imaging identified new findings in 65.2% of patients, which led to management changes in 65.8% of patients. CT imaging of the chest yielded the highest diagnostic usefulness, with new findings in 92.2% of patients and management changes in 64.1% of patients. The suspected cause of arrest was identified in 20.5% of CT scans. POCUS was performed in 264 patients (76.5%), most commonly cardiac (98.1%) and chest (70.8%) POCUS. New findings were identified in 57.6% of POCUS studies, and management changes resulted from 41.3% of POCUS images. POCUS identified the suspected arrest cause in 19.3% of patients. Only 1 adverse event occurred, a cardiac arrest during CT imaging (0.3% overall).

interpretationOur results show that among survivors of IHCA, CT imaging and POCUS frequently identified new pathologic features, including suspected arrest causes, with subsequent management changes in a substantial proportion of patients. Chest CT imaging demonstrated particularly high diagnostic yield, whereas POCUS provided timely bedside information. Both methods seem valuable in the early post-ROSC period, with rare but notable risks during CT imaging transport.

Indexed as

Heart ArrestPoint-of-Care SystemsTomography, X-Ray ComputedAgedCardiopulmonary ResuscitationFemaleHumansMaleMiddle AgedRetrospective StudiesUltrasonographycardiac arrestCTpoint-of-care ultrasound

Identifiers

PMID41833810
PMCPMC13245469

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.