Evidence map›Paper›PMID 41833691›Full record

ArticleSLAS technology2026

Engineering integrated evaporation solutions: Harmonizing manual approaches with automated laboratory workflows.

Pranav Bende, Anthony Garrison, Manan Luthra, Vijaya Krishna Veerisetty, Meghav Verma, Alexander G Godfrey, Dave Calabrese, Cullen Klein, Aco Radujevic, Thierry Masquelin and 6 more

Abstract read
In one paragraph

Article in SLAS technology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Pranav BendeNational Center for Advancing Translational Sciences, United States. Electronic address: pranav.bende@nih.gov.
Anthony GarrisonNational Center for Advancing Translational Sciences, United States.
Manan LuthraNational Center for Advancing Translational Sciences, United States.
Vijaya Krishna VeerisettyNational Center for Advancing Translational Sciences, United States.
Meghav VermaNational Center for Advancing Translational Sciences, United States.
Alexander G GodfreyNational Center for Advancing Translational Sciences, United States.
Dave CalabreseNational Center for Advancing Translational Sciences, United States.
Cullen KleinNational Center for Advancing Translational Sciences, United States.
Aco RadujevicNational Center for Advancing Translational Sciences, United States.
Thierry MasquelinNational Center for Advancing Translational Sciences, United States.
Savannah WoodNational Center for Advancing Translational Sciences, United States.
Victoria UjahNational Center for Advancing Translational Sciences, United States.
Samarjit PatnaikNational Center for Advancing Translational Sciences, United States.
Vidushi SharmaNational Center for Advancing Translational Sciences, United States.
Samuel G MichaelNational Center for Advancing Translational Sciences, United States.
Carleen Klumpp-ThomasNational Center for Advancing Translational Sciences, United States.

Funding

Intramural NIH HHS Z99 TR999999
6 · The paper itself

Abstract

Solvent evaporation, a ubiquitous yet often limiting step in chemical synthesis, routinely creates critical bottlenecks in research workflows. We introduce a novel benchtop solvent evaporation platform engineered to dramatically accelerate this process within a standard fume hood. Designed with flexible hardware and software architecture, this system is primed for autonomous control via Python scripting, transitioning from its current manual operation to fully automated capabilities. The platform offers two versatile configurations: a single-container evaporator for individual sample precision and a batch evaporator for high-throughput, simultaneous processing of multiple vials. Both variants feature a custom-designed, chemically inert 3D-printed adapter, equipped with precise compressed nitrogen and air inlet ports, alongside an efficient exhaust. Rapid and uniform solvent removal is achieved through a synergistic approach: integrated heating pads maintain optimal temperature in the vial block, while pressurized nitrogen is directed through uniquely helical channels within the adapter, generating a powerful vortex that significantly accelerates evaporation. Rigorous studies confirm the platform's robust and uniform solvent removal performance, conclusively demonstrating its potential to fundamentally alleviate key bottlenecks in chemical synthesis, thereby enhancing productivity and accelerating discovery. This innovative system represents a vital step towards fully automated and efficient chemical laboratories.

Indexed as

Automation, LaboratorySolventsWorkflowLaboratoriesVolatilizationSolventsAutomation friendlyBatch evaporationBenchtop compact platformCustom lab equipmentExperiment designHelical evaporationHigh-throughput processingLaboratory automationReproducibilitySolvent concentrationSolvent evaporationVortex evaporation

Identifiers

PMID41833691
PMCPMC13107995

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.