Evidence map›Paper›PMID 41832604›Full record

ArticleBiophysical journal2026

Biophysical and structural analysis of human green cone opsin.

Weekie Yao, Jonathan F Fay, David L Farrens

Abstract read
In one paragraph

Article in Biophysical journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Weekie YaoDepartment of Chemical Physiology and Biochemistry, Oregon Health & Science University, Portland, Oregon.
Jonathan F FayDepartment of Biochemistry and Molecular Biology, University of Maryland Baltimore, Baltimore, Maryland.
David L FarrensDepartment of Chemical Physiology and Biochemistry, Oregon Health & Science University, Portland, Oregon. Electronic address: farrensd@ohsu.edu.

Funding

Pacific Northwest Center for Cryo-EM - Screening supplementU24GM129547 · NIGMS · OREGON HEALTH & SCIENCE UNIVERSITY · PI EVANS, JAMES E, GOUAUX, JAMES E · 2018 to 2023
$54.8M
Structural Dynamics in Rhodopsin Activation and AttenuationR01EY029343 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI David L Farrens · 2019 to 2026
$2.9M
NEI NIH HHS R01 EY029343NIGMS NIH HHS U24 GM129547
6 · The paper itself

Abstract

We describe a straightforward method for purifying and optimizing human green cone opsin (GCO), which we then used for biophysical and structural studies of a GCO mutant, GCO

Indexed as

Biophysical PhenomenaCone OpsinsHumansModels, MolecularProtein BindingProtein ConformationCone Opsins

Identifiers

PMID41832604
PMCPMC13318088

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.