Evidence map›Paper›PMID 41832528›Full record

ArticleInternational journal of health geographics2026

What is rural? Examining the relationship between human populations and their inter-connectedness in the context of communicable disease transmission.

Cassandra Boutelle, Patrick Corbett, Andrew Gibson, Frederic Lohr, Catherine Swedberg, Jesse Blanton, Ryan Wallace

Abstract read
In one paragraph

Article in International journal of health geographics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Cassandra Boutelle *United States Centers for Disease Control and Prevention, Poxvirus and Rabies Branch, 1600 Clifton Ave, Atlanta, GA, USA. cassie@wvs.org.uk.
Patrick Corbett *United States Centers for Disease Control and Prevention, Poxvirus and Rabies Branch, 1600 Clifton Ave, Atlanta, GA, USA.
Andrew GibsonMission Rabies, 4 Castle Street, Cranborne, Dorset, BH21 5PZ, UK.
Frederic LohrMission Rabies, 4 Castle Street, Cranborne, Dorset, BH21 5PZ, UK.
Catherine SwedbergUnited States Centers for Disease Control and Prevention, Poxvirus and Rabies Branch, 1600 Clifton Ave, Atlanta, GA, USA.
Jesse BlantonUnited States Centers for Disease Control and Prevention, Poxvirus and Rabies Branch, 1600 Clifton Ave, Atlanta, GA, USA.
Ryan WallaceUnited States Centers for Disease Control and Prevention, Poxvirus and Rabies Branch, 1600 Clifton Ave, Atlanta, GA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRurality and urbanicity are recognized determinants of public health outcomes that influence policy and resource allocation. However, many commonly used methods to classify the rural-urban continuum, such as the Rural-Urban Commuting Area (RUCA) codes, lack applicability in low and middle-income countries (LMICs). This study introduces the Settlement Type and Road Connectivity (STARC) methodology, which offers a standardized and accessible approach to classifying regions along the rural-urban continuum.

methodsLeveraging open-source software and readily available data, STARC generates detailed maps composed of small hexagonal polygons. Each hexagon unit is assigned one of twenty-four categorical STARC codes based on its estimated population density and community-based road connectivity. Collectively, the hexagon units comprise the base layer STARC map. Additional metrics related to disease transmission can be overlayed onto each STARC hexagon unit in order to perform hotspot analysis via the local Gi* statistic and create transmission zones. All operations within the STARC process have been packaged into a publicly available tool on GitHub.

resultsTo demonstrate the STARC process, we executed the full STARC methodology at the local, national, and regional level for study areas in Central and Western Africa. Free roaming dog densities were selected as the metric of interest in order to identify hotspots and transmission clusters for dog-mediated rabies.

conclusionsIn our analysis we demonstrate that STARC codes can be used to standardize the rural-urban continuum and better understand the distribution of connectedness of populations. Hotspot analysis of free roaming dogs in several African countries shows that dog populations, a key factor in rabies transmission, are often concentrated in urban and peri-urban areas, many of which span domestic and international boundaries. By providing a dynamic and data-driven approach to understanding the rural-urban landscape, STARC offers a valuable tool for public health interventions in LMICs.

Indexed as

Communicable DiseasesRural PopulationAnimalsDog DiseasesDogsHumansPopulation DensityRabiesUrban PopulationCommunicable diseaseHotspot analysisPopulation estimationRisk mapUrbanicity

Identifiers

PMID41832528
PMCPMC13104494

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.