Evidence map›Paper›PMID 41832488›Full record

ArticleBMC ophthalmology2026

A clinical prediction tool for ocular hypertension following silicone oil tamponade in rhegmatogenous retinal detachment.

Huan Ju, Xuefeng Qin, Xing Wang, Lingyi Jin, Yuanyuan Wu, Qingyue Luo, Huan Zhou, Ni Zhang, Hui Peng

Abstract read
In one paragraph

Article in BMC ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Huan Ju *Department of Ophthalmology, The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory for the Prevention and Treatment of Major Blinding Eye Diseases, No.1, Youyi Road, Yuzhong District, Chongqing, 400016, China.
Xuefeng Qin *Department of Ophthalmology, The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory for the Prevention and Treatment of Major Blinding Eye Diseases, No.1, Youyi Road, Yuzhong District, Chongqing, 400016, China.
Xing WangDepartment of Ophthalmology, The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory for the Prevention and Treatment of Major Blinding Eye Diseases, No.1, Youyi Road, Yuzhong District, Chongqing, 400016, China.
Lingyi JinDepartment of Ophthalmology, The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory for the Prevention and Treatment of Major Blinding Eye Diseases, No.1, Youyi Road, Yuzhong District, Chongqing, 400016, China.
Yuanyuan WuDepartment of Ophthalmology, The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory for the Prevention and Treatment of Major Blinding Eye Diseases, No.1, Youyi Road, Yuzhong District, Chongqing, 400016, China.
Qingyue LuoDepartment of Ophthalmology, The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory for the Prevention and Treatment of Major Blinding Eye Diseases, No.1, Youyi Road, Yuzhong District, Chongqing, 400016, China.
Huan ZhouDepartment of Ophthalmology, The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory for the Prevention and Treatment of Major Blinding Eye Diseases, No.1, Youyi Road, Yuzhong District, Chongqing, 400016, China.
Ni ZhangDepartment of Ophthalmology, The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory for the Prevention and Treatment of Major Blinding Eye Diseases, No.1, Youyi Road, Yuzhong District, Chongqing, 400016, China. 11805347@qq.com.ORCID http://orcid.org/0000-0002-6340-9239
Hui PengDepartment of Ophthalmology, The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory for the Prevention and Treatment of Major Blinding Eye Diseases, No.1, Youyi Road, Yuzhong District, Chongqing, 400016, China. pengh9@sina.com.ORCID http://orcid.org/0000-0003-4758-3752

Funding

Natural Science Foundation of Chongqing, China CSTB2024NSCQ-MSX0705
6 · The paper itself

Abstract

introductionThis study aimed to develop predictive models for identifying risk factors of postoperative IOP elevation in patients with rhegmatogenous retinal detachment (RRD) following silicone oil (SO) tamponade.

methodsThis retrospective study involved 533 RRD patients treated at the First Affiliated Hospital of Chongqing Medical University between September 1, 2024, and June 19, 2025. IOP was measured postoperatively on day 1, week 1, and months 1, 3, 6, and before SO removal using the non-contact tonometer Corvis Scheimpflug Technology (Corvis ST, OCULUS, Wetzlar, Germany) to acquire biomechanically corrected IOP (bIOP). Multiple machine learning (ML) models and one nomogram were constructed using demographic, clinical, and surgical factors.

resultsPostoperatively, 57.8% of patients developed elevated intraocular pressure (IOP), with 81.5% occurring within two weeks. A Stepwise GLM [forward] + SVM model based on clinical features outperformed the Nomogram (AUC 0.761 vs. 0.729). The top five predictors were axial length (AL), age, white-to-white corneal diameter (WTW), proliferative vitreoretinopathy (PVR), and central corneal thickness (CCT).

conclusionIn RRD patients receiving silicone oil tamponade, AL, age, WTW, PVR, and CCT were closely associated with postoperative IOP elevation. The ML models outperformed nomogram in accuracy and clinical interpretability, offering a reliable tool utilizing bIOP for early IOP risk assessment and postoperative management in RRD patients. Their integration of anatomical and biometric features supports real-world clinical deployment and individualized care planning.

Indexed as

EndotamponadeOcular HypertensionPostoperative ComplicationsRetinal DetachmentSilicone OilsVitrectomyAdultAgedFemaleHumansIntraocular PressureMaleMiddle AgedNomogramsPrediction AlgorithmsPredictive Learning ModelsSilicone OilsMachine learningNomogramOcular hypertensionRhegmatogenous retinal detachmentSilicone oils

Identifiers

PMID41832488
PMCPMC13101243

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.