Evidence map›Paper›PMID 41832431›Full record

ArticleBMC emergency medicine2026

Epidemiological and clinical characteristics of drug-related poisoning presentations to the emergency department: a retrospective analysis.

İbrahim Sarbay, Yunus Emre Ayhan, Taha Abdurrahim Yilmaz, Hazal Karadag, Meltem Urlu, Begum Ezelsoy, Günes Eskidemir, Melike Mercan Baspinar, Mustafa Calik

Abstract read
In one paragraph

Article in BMC emergency medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

İbrahim Sarbay *Emergency Department, Gaziosmanpaşa Training and Research Hospital, Istanbul, Türkiye. ibrahimsar@gmail.com.ORCID 0000-0001-8804-2501
Yunus Emre Ayhan *Prof. Dr. Cemil Taşcıoğlu City Hospital, Clinical Pharmacy, Istanbul, Türkiye.ORCID 0000-0001-6093-0849
Taha Abdurrahim YilmazEmergency Department, Gaziosmanpaşa Training and Research Hospital, Istanbul, Türkiye.ORCID 0009-0003-6960-497X
Hazal KaradagEmergency Department, Gaziosmanpaşa Training and Research Hospital, Istanbul, Türkiye.ORCID 0000-0002-3246-5430
Meltem UrluEmergency Department, Gaziosmanpaşa Training and Research Hospital, Istanbul, Türkiye.ORCID 0009-0003-0208-8886
Begum EzelsoyEmergency Department, Gaziosmanpaşa Training and Research Hospital, Istanbul, Türkiye.ORCID 0009-0008-3595-8952
Günes EskidemirCritical Care Unit, Gaziosmanpaşa Training and Research Hospital, Istanbul, Türkiye.ORCID 0000-0002-7998-7690
Melike Mercan BaspinarFamily Medicine Department, Gaziosmanpaşa Training and Research Hospital, Istanbul, Türkiye.ORCID 0000-0003-3183-3438
Mustafa CalikEmergency Department, Gaziosmanpaşa Training and Research Hospital, Istanbul, Türkiye.ORCID 0000-0002-3184-2943

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesDrug-related poisoning remains a significant public health problem and is a common cause of emergency department (ED) admissions worldwide. The primary objective of this study was to determine the demographic characteristics of patients, the causes of poisoning, and the drug groups responsible for poisoning.

methodsThis retrospective study included adult patients (≥ 18 years) who presented to a tertiary-care ED with clinically confirmed drug-related poisoning between January 1, 2023, and October 31, 2025. Demographic data, poisoning characteristics, clinical findings, treatment modalities, and outcomes were extracted from electronic medical records. Poisoning severity was assessed using the Poisoning Severity Score (PSS). Univariate and multivariable binary logistic regression analyses were performed to identify factors associated with ICU admission.

resultsA total of 488 patients were included. Analgesics (including non-steroidal anti-inflammatory drugs) and antidepressants were the most frequently implicated drug classes. ICU admission from the ED was required in 49 patients (10.0%), while overall mortality was low (0.2%). In univariate analyses, higher PSS scores, lower Glasgow Coma Scale scores, higher total ingested tablet counts, and multiple-drug ingestion were associated with ICU admission. In multivariable analysis, both the poisoning severity score (adjusted OR 2.53, 95% CI 1.56–4.12; p < 0.001) and the total ingested dose, expressed as tablet count (adjusted OR 1.03, 95% CI 1.01–1.04; p = 0.001), remained independently associated with ICU admission.

conclusionsDrug-related poisoning is a frequent reason for ED presentation, predominantly resulting from intentional exposure. The poisoning severity score is a valuable tool for early risk stratification and identification of patients at increased risk for ICU admission.

Indexed as

Emergency Service, HospitalPoisoningAdultAgedEmergency Room VisitsFemaleGlasgow Coma ScaleHumansIntensive Care UnitsMaleMiddle AgedRetrospective StudiesSeverity of Illness IndexDrug-related poisoningEmergency departmentEpidemiologyIntensive care unitPoisoning severity score

Identifiers

PMID41832431
PMCPMC13101304

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.