Observational studyBMC anesthesiology2026
Ultrasonographic evaluation of intraoperative optic nerve sheath diameter changes in patients undergoing laparoscopic surgery.
Observational study in BMC anesthesiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06209034 (Ultrasonographic Evaluation of Intraoperative Optic Nerve Sheath Diameter Changes in Patients Undergoing Laparoscopic Surgery), which is not on this map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Ultrasonographic Evaluation of Intraoperative Optic Nerve Sheath Diameter Changes in Patients Undergoing Laparoscopic Surgery
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLaparoscopic surgery offers several advantages such as reduced postoperative pain and faster recovery; however, the establishment of pneumoperitoneum has the potential to transiently increase intracranial pressure (ICP). Ultrasonographic measurement of the optic nerve sheath diameter (ONSD) provides a reliable noninvasive indicator of ICP changes. This study aimed to evaluate ONSD measurements, which may reflect intraoperative ICP changes during laparoscopic upper abdominal surgery performed in the reverse Trendelenburg position, and to assess the specific effects of pneumoperitoneum.
methodsFifty-five patients with ASA physical status I-III who undergoing elective laparoscopic upper abdominal surgery were prospectively enrolled. Bilateral ONSD measurements were performed at four time points: after induction of anesthesia (T0), 10 min (T1), and 60 min (T2) after the establishment of pneumoperitoneum, and 10 min after desufflation (T3). Respiratory and hemodynamic parameters were recorded simultaneously.
resultsMean ONSD values increased significantly at both 10 and 60 min of pneumoperitoneum compared to baseline (p < 0.001) and remained elevated even after desufflation (p < 0.01). No significant difference was observed between T1 and T2. Peak and plateau pressures increased while compliance decreased during pneumoperitoneum (p < 0.001).
conclusionPneumoperitoneum during laparoscopic upper abdominal surgery causes a significant yet transient increase in ONSD. Although ONSD values showed a partial decrease after desufflation, they remained higher than baseline measurements but within clinically acceptable and non-critical ranges. Continuous intraoperative ultrasonographic ONSD monitoring may provide real-time insight into intracranial dynamics, particularly in patients at risk for elevated ICP. Further studies are warranted to clarify the underlying multifactorial mechanisms and determine the clinical significance of ONSD alterations. CLINICAL TRIALS REGISTRATION: NCT06209034, Registered January 6, 2024. (Retrospectively registered). ETHICAL COMMITTEE APPROVAL: GOKAEK-2023/19.12.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.