Evidence map›Paper›PMID 41832362›Full record

Trial reportAnnals of surgical oncology2026

Acceptability and Feasibility of a Virtual Multimodal (P)Rehabilitation Programme for Gastrointestinal Cancer Patients: The PRIORITY-CONNECT 2 Pilot Randomised Controlled Trial.

Jack Reeves, Cherry Koh, Allan Ben Smith, Helen Mohan, Sharon Carey, Stephen Smith, Thomas Poulton, Vicki Patton, Kate White, Liliana Laranjo and 35 more

Registry-linked trialAbstract readRandomized Controlled TrialMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Annals of surgical oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06212700 (Virtual Multimodal Hub for Patients Undergoing Major Gastrointestinal Cancer Surgery - PRIORITY-CONNECT 2 Pilot Randomised Type I Hybrid Effectiveness-Implementation Trial), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06212700 naunknown statusnot on this map

Virtual Multimodal Hub for Patients Undergoing Major Gastrointestinal Cancer Surgery - PRIORITY-CONNECT 2 Pilot Randomised Type I Hybrid Effectiveness-Implementation Trial

TypeinterventionalSponsorSurgical Outcomes Research Centre (SOuRCe)Ran2024 to 2025Enrolled20ConditionsLiver Cancer, Pancreas Cancer, Oesophageal Cancer, Gastric CancerArmsPreoperative Exercise, Postoperative Exercise, Preoperative Nutrition, Postoperative Nutrition, Preoperative Psychology
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

45 authors.

Jack ReevesSurgical Outcomes Research Centre (SOuRCe), Royal Prince Alfred Hospital, Sydney, NSW, Australia.
Cherry KohSurgical Outcomes Research Centre (SOuRCe), Royal Prince Alfred Hospital, Sydney, NSW, Australia.
Allan Ben SmithThe Daffodil Centre, The University of Sydney, and Cancer Council NSW, Sydney, Australia.
Helen MohanDepartment of Cancer Surgery, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
Sharon CareySurgical Outcomes Research Centre (SOuRCe), Royal Prince Alfred Hospital, Sydney, NSW, Australia.
Stephen SmithDepartment of Colorectal Surgery, John Hunter Hospital, Sydney, NSW, Australia.
Thomas PoultonDepartment of Anaesthesia, Perioperative Medicine, and Pain Medicine, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
Vicki PattonFaculty of Health Sciences, Curtin School of Nursing, Curtin University, Perth, WA, Australia.
Kate WhiteThe Daffodil Centre, The University of Sydney, and Cancer Council NSW, Sydney, Australia.
Liliana LaranjoFaculty of Medicine and Health, Westmead Applied Research Centre, The University of Sydney, Sydney, NSW, Australia.
Mbathio DiengNHMRC Clinical Trials Centre, The University of Sydney, Sydney, NSW, Australia.
Xiaoqiu LiuBiostatistics and Data Science Division, The George Institute for Global Health, University of New South Wales, Sydney, NSW, Australia.
Linda DenehyDepartment of Physiotherapy, The University of Melbourne, Melbourne, VIC, Australia.
Kate WilsonSurgical Outcomes Research Centre (SOuRCe), Royal Prince Alfred Hospital, Sydney, NSW, Australia.
Margaret Allman-FarinelliFaculty of Medicine and Health, Sydney Nursing School, The University of Sydney, Sydney, NSW, Australia.
Phyllis ButowPsycho-Oncology Co-operative Research Group (PoCoG), The University of Sydney, Sydney, NSW, Australia.
Bernhard RiedelDepartment of Anaesthesia, Perioperative Medicine, and Pain Medicine, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
Rachael L MortonNHMRC Clinical Trials Centre, The University of Sydney, Sydney, NSW, Australia.
Leanne HassettFaculty of Medicine and Health, Sydney Health Partners, Sydney School of Health Sciences, The University of Sydney, Sydney, NSW, Australia.
Qiang LiBiostatistics and Data Science Division, The George Institute for Global Health, University of New South Wales, Sydney, NSW, Australia.
Kim DelbaereFalls, Balance and Injury Research Centre, Neuroscience Research Australia (NeuRA), Sydney, NSW, Australia.
Olivia MartinRoyal Prince Alfred Hospital, Sydney, NSW, Australia.
Haryana M DhillonFaculty of Science, School of Psychology, Psycho-Oncology Cooperative Research Group, University of Sydney, Sydney, NSW, Australia.
Briana ShailerRoyal Prince Alfred Hospital, Sydney, NSW, Australia.
Gaynor BeardsworthRoyal Prince Alfred Hospital, Sydney, NSW, Australia.
Marine SalterRoyal Prince Alfred Hospital, Sydney, NSW, Australia.
Kathryn CherryRoyal Prince Alfred Hospital, Sydney, NSW, Australia.
Freya RubieRoyal Prince Alfred Hospital, Sydney, NSW, Australia.
Lauren ReeceRoyal Prince Alfred Hospital, Sydney, NSW, Australia.
Aveline ChanRoyal Prince Alfred Hospital, Sydney, NSW, Australia.
Rihan ShahabFaculty of Medicine and Health, Sydney Nursing School, The University of Sydney, Sydney, NSW, Australia.
Olivia DwyerRoyal Prince Alfred Hospital, Sydney, NSW, Australia.
Kaylene PringRoyal Prince Alfred Hospital, Sydney, NSW, Australia.
Derek CunninghamCancer Voices NSW, Sydney, NSW, Australia.
Kym SheehanCancer Voices NSW, Sydney, NSW, Australia.
Gino IoriCancer Voices NSW, Sydney, NSW, Australia.
Rika JohnanderCancer Voices NSW, Sydney, NSW, Australia.
Claire JeonSurgical Outcomes Research Centre (SOuRCe), Royal Prince Alfred Hospital, Sydney, NSW, Australia.
Nicholas HirstSurgical Outcomes Research Centre (SOuRCe), Royal Prince Alfred Hospital, Sydney, NSW, Australia.
Sascha KarunaratneSurgical Outcomes Research Centre (SOuRCe), Royal Prince Alfred Hospital, Sydney, NSW, Australia.
Annie ZhouFaculty of Science, School of Psychology, University of Sydney, Sydney, NSW, Australia.
Owen HutchingsSydney Local Health District Virtual Hospital, Sydney, NSW, Australia.
Michael SolomonSurgical Outcomes Research Centre (SOuRCe), Royal Prince Alfred Hospital, Sydney, NSW, Australia.
Daniel SteffensSurgical Outcomes Research Centre (SOuRCe), Royal Prince Alfred Hospital, Sydney, NSW, Australia. Daniel.Steffens@health.nsw.gov.au.ORCID http://orcid.org/0000-0002-9715-860X
PRIORITY-CONNECT Collaborators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSurgery is a mainstay of treatment for gastrointestinal cancers, yet it often leads to postoperative complications and poorer health outcomes. (P)rehabilitation may improve postoperative outcomes; however, optimal delivery modes remain unclear. Traditional face-to-face models may be inaccessible for patients in geographically dispersed countries. This pilot trial was designed to determine the feasibility and acceptability of a virtual multimodal (p)rehabilitation programme in patients undergoing gastrointestinal cancer surgery.

methodsThe PRIORITY-CONNECT 2 Pilot trial was a multicentre, assessor-blinded, randomised controlled feasibility pilot trial. Consenting adults scheduled for gastrointestinal cancer surgery were randomised 1:1 to receive a virtual multimodal (p)rehabilitation programme (up to 6 weeks preoperatively and 3 months postoperatively) plus usual care or usual care alone. The virtual hub provided specialised multidisciplinary care by a team that included a physiotherapist, psychologist, dietitian, specialist nurse, social worker, and geriatrician. Primary outcomes included intervention feasibility (in terms of uptake, retention, and adherence) and acceptability. Secondary outcomes included postoperative complications within 30 days following surgery, health-related quality of life, and days at home within 30 and 90 days of surgery.

resultsWe randomised 20 participants (intervention n = 11, control n = 9). Uptake among eligible participants was 65%, retention 95%, and adherence 74%. Overall satisfaction with the programme was high; 78% of respondents reported that they were either "satisfied" or "extremely satisfied."

conclusionsThe results of this pilot trial demonstrate both feasibility and acceptability of the intervention. The full-scale PRIORITY-CONNECT 2 Trial will determine the effectiveness of a virtual multimodal (p)rehabilitation programme for patients undergoing colorectal cancer surgery. Trial registration This trial was registered prospectively with the National Library of Medicine ClinicalTrials.gov Registry (NCT06212700) on 8th January 2024.

Indexed as

Gastrointestinal NeoplasmsPatient Acceptance of Health CarePostoperative ComplicationsQuality of LifeAdultAgedFeasibility StudiesFemaleFollow-Up StudiesHumansMaleMiddle AgedPilot ProjectsPrognosisGastrointestinal cancerPrehabilitationRandomised controlled trialRehabilitationTtelehealth

Identifiers

PMID41832362
PMCPMC13179161

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.