ArticleAnnals of surgical oncology2026
Single-Port Endoscopic Nipple-Sparing Mastectomy Using a Handheld Motorized Articulating System: Technical Description and Initial Outcomes.
Article in Annals of surgical oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Single-port robot-assisted nipple-sparing mastectomy: a systematic review.Journal of robotic surgery · 2026Pooled it
- Comment on: "Robotic and Endoscopic Minimally Invasive Breast Surgery: A Narrative Synthesis on Divergent Global Adoption and Emerging Trends".European journal of breast health · 2026Article
- Comment on: "Three Strategic Pillars for Implementing Endoscopic Nipple-Sparing Mastectomy".JSLS : Journal of the Society of Laparoendoscopic SurgeonsArticle
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEndoscopic nipple-sparing mastectomy (NSM) offers excellent cosmetic outcomes but remains technically demanding with conventional straight laparoscopic instruments, particularly in the medial, inferior, and retroareolar regions. The HandX™ (HumanTouch Surgical Ltd, Israel) is a 5-mm handheld, software-driven motorized articulating system that provides wrist-like motion. Its application in endoscopic breast surgery has not been previously reported. PATIENTS AND
methodsWe present the first clinical use of this articulating system in single-port endoscopic NSM with immediate implant-based reconstruction. Two patients-one therapeutic case following complete clinical response to neoadjuvant chemotherapy and one bilateral prophylactic case-underwent NSM through a lateral incision using a standard single-port system. The articulating monopolar scissors were used to complete the superior, medial, inferior, and retroareolar dissection under CO
resultsAll procedures were completed successfully without intraoperative complications. Operative times were 240 min for the unilateral case, including axillary procedure, and 250 min for the bilateral case. Blood loss was minimal, and both patients were discharged within 48 h. Drains were removed on postoperative day 7. No early (30-day) or late (90-day) complications occurred. Final pathology demonstrated a pathologic complete response in the therapeutic case and multifocal atypical ductal hyperplasia in the prophylactic case.
conclusionsSingle-port endoscopic NSM using a software-driven motorized articulating system is technically feasible and facilitates dissection in challenging regions. This technique represents a minimally invasive approach positioned between fully robotic systems and endoscopic techniques, and warrants further evaluation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.