Evidence map›Paper›PMID 41831180›Full record

ArticleDiscover nano2026

Chitosan nanoparticles loaded with Cosmos bipinnatus essential oil for sustainable management of plant parasitic nematodes.

Himani Karakoti, Ravendra Kumar, Shivang Joshi, Pooja Bargali, Sneh Gautam, Fábio Cardoso, Mozaniel Santana de Oliveira, Shilpi Rawat, Dharmendra Singh Rawat

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Discover nano, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Himani KarakotiDepartment of Chemistry, College of Basic Sciences and Humanities, G.B. Pant University of Agriculture and Technology, Pantnagar, U.S. Nagar, Uttarakhand, 263145 , India.ORCID http://orcid.org/0000-0003-1407-226X
Ravendra KumarDepartment of Chemistry, College of Basic Sciences and Humanities, G.B. Pant University of Agriculture and Technology, Pantnagar, U.S. Nagar, Uttarakhand, 263145 , India. ravichemistry.kumar@gmail.com.
Shivang JoshiDepartment of Chemistry, College of Basic Sciences and Humanities, G.B. Pant University of Agriculture and Technology, Pantnagar, U.S. Nagar, Uttarakhand, 263145 , India.
Pooja BargaliDepartment of Chemistry, College of Basic Sciences and Humanities, G.B. Pant University of Agriculture and Technology, Pantnagar, U.S. Nagar, Uttarakhand, 263145 , India.
Sneh GautamDepartment of Molecular Biology & Genetic Engineering, College of Basic Sciences and Humanities, G.B. Pant University of Agriculture and Technology, Pantnagar, U.S. Nagar, Uttarakhand, 263145, India.
Fábio CardosoFaculty of Chemistry, Institute of Natural Science, Federal University of Pará, Belém, 66075110, Brazil.
Mozaniel Santana de OliveiraLaboratory of Pharmacology of Inflammation and Behavior, Graduate Program in Pharmaceutical Sciences, Institute of Health Sciences, Federal University of Pará, Belém, 66075110, Brazil. mozaniel@ufpa.br.
Shilpi RawatDepartment of Plant Pathology, College of Agriculture, G.B. Pant University of Agriculture and Technology, Pantnagar, U.S. Nagar, Uttarakhand, 263145, India.
Dharmendra Singh RawatDepartment of Biological Sciences, College of Basic Sciences and Humanities, G.B. Pant University of Agriculture and Technology, Pantnagar, U.S. Nagar, 263145, Uttarakhand, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The sustainable management of plant-parasitic nematodes is a growing concern in agriculture due to the limitations of synthetic nematicides, such as environmental toxicity and resistance development. This study reports, for the first time, the encapsulation of Cosmos bipinnatus essential oil (CAO) into chitosan nanoparticles (CSNPs) for nematicidal application against Meloidogyne incognita. GC-MS analysis identified cis-β-ocimene, cosmene, germacrene D, sabinene, and β-pinene as the dominant constituents. The resulting CSNPs exhibited favourable physicochemical characteristics (mean diameter: 91.2 nm; encapsulation efficiency: 83%) and a pH-responsive controlled release profile. In vitro assays revealed that at the highest concentration (1000 µg/mL), CSNPs demonstrated significantly higher nematode mortality (100%) and egg hatching inhibition (100%) than CAO (77% mortality and 89.04% egg hatching inhibition) and comparable to the commercial nematicide Nimitz at 96 h. Enhanced acetylcholinesterase (AChE) inhibition by CSNPs (IC

Indexed as

AChE inhibitionCosmos bipinnatusMeloidogyne incognitaMolecular dockingNanoparticle

Identifiers

PMID41831180
PMCPMC12988939

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.