Evidence map›Paper›PMID 41831084›Full record

ArticleTropical animal health and production2026

Influence of maternal or neonatal Vitamin A injection on calf performance and muscle transcriptomics in the cow-calf phase.

J M Oliveira, D R Casagrande, S A S Laura, A H A Horta, A S Miranda, T R S Gionbelli, L H L Chalfun, M M Ladeira

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In one paragraph

Article in Tropical animal health and production, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

J M OliveiraDepartment of Animal Science, Universidade Federal de Lavras, Lavras, Minas Gerais, 37200-900, Brazil.
D R CasagrandeDepartment of Animal Science, Universidade Federal de Lavras, Lavras, Minas Gerais, 37200-900, Brazil.
S A S LauraDepartment of Animal Science, Universidade Federal de Lavras, Lavras, Minas Gerais, 37200-900, Brazil.
A H A HortaDepartment of Animal Science, Universidade Federal de Lavras, Lavras, Minas Gerais, 37200-900, Brazil.
A S MirandaDepartment of Animal Science, Universidade Federal de Lavras, Lavras, Minas Gerais, 37200-900, Brazil.
T R S GionbelliDepartment of Animal Science, Universidade Federal de Lavras, Lavras, Minas Gerais, 37200-900, Brazil.
L H L ChalfunCentro Universitário de Lavras - Unilavras, Lavras, Minas Gerais, 37203-593, Brazil.
M M LadeiraDepartment of Animal Science, Universidade Federal de Lavras, Lavras, Minas Gerais, 37200-900, Brazil. mladeira@ufla.br.ORCID http://orcid.org/0000-0002-1585-8486

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigated the effects of vitamin A (VA) injection on growth performance, muscle development, and skeletal muscle transcriptomics in calves during the cow-calf phase. Pregnant cows at 250 days of gestation were randomly assigned to one of three treatments: control (CON; no VA injection), VA injection in cows at 250 d of gestation (VAcow), or VA injections in calves at birth and 60 days of age (VAcalf). Calves were weighed at 60 d and weaning. Carcass ultrasound and muscle biopsy were conducted at weaning. Gene expressions were analyzed by RT-qPCR. Male calves in the VAcow group had higher (P = 0.01) ADG than Control males and VA-treated females. Weaning BW was greater (P < 0.01) in VAcalf and VAcow males compared to Control males and VA-treated females. Gene expression analysis revealed that RARA, MYF5, CEBPA, and DLK1 were higher (P ≤ 0.05) expressed in Control and VAcow calves than in VAcalf calves. Expressions of ZNF423 and RXRA tended to be greater (P ≤ 0.09) in VAcow males than in VAcalf males and VA-treated females. The expression of PAX7 was higher (P < 0.01) in VAcow males than in all other groups. Also, IGFR1 expression tended to be greater (P = 0.07) in VAcow males than in Control and VAcalf males and VAcalf females. In conclusion, VA injection during late gestation or early postnatal life improved growth of male calves. Maternal VA injection had a more pronounced effect on muscle gene expression, particularly in male calves.

Indexed as

Muscle DevelopmentMuscle, SkeletalTranscriptomeVitamin AAnimalsAnimals, NewbornCattleFemaleMalePregnancyVitamin AAdipogenesisFetal programmingMuscle growthMyogenesisNeonatal programmingRetinoic acid

Identifiers

PMID41831084
PMCPMC12988903

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.