Evidence map›Paper›PMID 41830638›Full record

ArticleJournal of medicinal chemistry2026

Engineering Antimicrobial Peptides via Motif Assembly for Combating Multidrug-Resistant Pathogens.

Sukhvir Kaur Bhangu, Fanyi Li, Rong Xu, Thirimadura Vishna Heshini Mendis, Nicholas G Welch, James Harris, John D Wade, Mohammed Akhter Hossain, Helmut Thissen, Wioleta Kowalczyk

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of medicinal chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sukhvir Kaur BhanguCommonwealth Scientific and Industrial Research Organisation (CSIRO), Manufacturing, Clayton, Victoria 3169, Australia.ORCID 0000-0002-9810-4304
Fanyi LiCommonwealth Scientific and Industrial Research Organisation (CSIRO), Manufacturing, Clayton, Victoria 3169, Australia.ORCID 0000-0002-1886-4857
Rong XuDepartment of Diabetes, School of Translational Medicine, Monash University, Melbourne, Victoria 3004, Australia.
Thirimadura Vishna Heshini MendisDepartment of Diabetes, School of Translational Medicine, Monash University, Melbourne, Victoria 3004, Australia.
Nicholas G WelchCommonwealth Scientific and Industrial Research Organisation (CSIRO), Manufacturing, Clayton, Victoria 3169, Australia.ORCID 0000-0001-8172-8252
James HarrisCommonwealth Scientific and Industrial Research Organisation (CSIRO), Manufacturing, Clayton, Victoria 3169, Australia.
John D WadeFlorey Institute of Neuroscience and Mental Health and Department of Biochemistry and Pharmacology, University of Melbourne, Parkville, Victoria 3010, Australia.ORCID 0000-0002-1352-6568
Mohammed Akhter HossainFlorey Institute of Neuroscience and Mental Health and Department of Biochemistry and Pharmacology, University of Melbourne, Parkville, Victoria 3010, Australia.ORCID 0000-0002-9961-0006
Helmut ThissenCommonwealth Scientific and Industrial Research Organisation (CSIRO), Manufacturing, Clayton, Victoria 3169, Australia.ORCID 0000-0002-3254-6855
Wioleta KowalczykCommonwealth Scientific and Industrial Research Organisation (CSIRO), Manufacturing, Clayton, Victoria 3169, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hybridization of common motifs from known antimicrobial peptides (AMPs) is a promising strategy for designing a new class of antimicrobial agents with improved activity. Herein, the machine learning-generated peptide sequence IIKLLGVLAKFVLGQ-NH

Indexed as

Anti-Bacterial AgentsAntimicrobial PeptidesDrug Resistance, Multiple, BacterialAcinetobacter baumanniiAmino Acid MotifsAmino Acid SequenceAnimalsBiofilmsGram-Negative BacteriaGram-Positive BacteriaHumansMicrobial Sensitivity TestsProtein EngineeringAnti-Bacterial AgentsAntimicrobial Peptides

Identifiers

PMID41830638
PMCPMC13036773

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.