Evidence map›Paper›PMID 41830438›Full record

ArticleThe journals of gerontology. Series B, Psychological sciences and social sciences2026

Caregiving responsibilities, living alone, and mental health among older women during a time of collective stress.

Yiwen Zhu, Laura Sampson, Justin G Farmer, Shaili C Jha, Archana Basu, Karestan C Koenen, Laura D Kubzansky

Abstract read
In one paragraph

Article in The journals of gerontology. Series B, Psychological sciences and social sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yiwen ZhuDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States.ORCID 0000-0002-3874-6671
Laura SampsonDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States.
Justin G FarmerDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States.
Shaili C JhaDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States.
Archana BasuDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States.ORCID 0000-0003-2585-868X
Karestan C KoenenDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States.
Laura D KubzanskyDepartment of Social and Behavioral Sciences, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, United States.ORCID 0000-0002-4039-2235

Funding

Life Course Cancer Epidemiology Cohort in WomenU01CA176726 · NCI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI ELIASSEN, A. HEATHER, WILLETT, WALTER C. · 2018 to 2025
$22.4M
Integrating lifecourse approaches, biologic and digital phenotypes in support of heart and lung disease epidemiologic researchU01HL145386 · NHLBI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI CHAVARRO, JORGE EDUARDO, MANSON, JOANN ELISABETH · 2019 to 2025
$17.8M
Training Program in Psychiatric Genetics and Translational ResearchT32MH017119 · NIMH · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI KARESTAN C KOENEN, Jukka-Pekka Onnela · 1985 to 2026
$8.9M
NCI NIH HHS U01 CA176726NHLBI NIH HHS U01 HL145386NIH HHS U01 CA176726NIH HHS U01 HL145386NIMH NIH HHS T32 MH017119
6 · The paper itself

Abstract

objectivesThe prevailing belief is that during times of heightened collective stress, the adverse effects of experiences such as caregiving and living alone on mental health are exacerbated. Whether this is true and the extent to which modifiable contextual factors still buffer their negative effects remain underexplored. Women are often disproportionately affected by the burdens of caregiving, and older adults face added challenges due to age-related social and health vulnerabilities. We examined prospective associations of caregiving responsibilities and living alone with mental health in a cohort of older women and evaluated the role of caregiving-related stress and social support.

methodsLongitudinal data were collected in a subsample of women from the Nurses' Health Study II (n = 27,646; mean age: 67), across seven time points during the COVID-19 pandemic. Participants self-reported caregiving responsibilities and living arrangements. Participants providing care also reported caregiving-related stress levels and social support levels. Seven mental health measures capturing psychological distress and positive psychological functioning were assessed 1-6 times over one year. Analyses accounted for multiple testing and key confounders.

resultsCompared to non-caregivers, caregivers not reporting stress had better mental health across measures (e.g., Odds Ratioanxiety = 0.8, 95% Confidence Interval = 0.75-0.85). Women living alone did not show worse mental health with adequate social support, relative to women living with others and adequately supported. DISCUSSION: Effects of caregiving responsibilities and living alone are not uniform, even during times of heightened stress. Caregiving stress and social support matter. Overlooking key contextual factors may lead to missed opportunities for prevention and intervention.

Indexed as

CaregiversCOVID-19Mental HealthStress, PsychologicalAgedFemaleHumansLongitudinal StudiesMiddle AgedPsychological DistressSocial SupportCaregiver stressPsychological distressSocial isolationSocial supportWell-being

Identifiers

PMID41830438
PMCPMC13120884

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.