Evidence map›Paper›PMID 41829816›Full record

ReviewPlants (Basel, Switzerland)2026

Early Plant Development as a Systems-Level Trait: Integrating Omics, Artificial Intelligence, and Emerging Biotechnologies.

Abdallah S Al-Sawa'eer, Ali Al-Samydai, Lama Odeh, Fatima Haj Ahmad, Renata Obekh, Yousef M Abd Elqader, Anas Khaleel, Ahmad M Al-Athamneh, Mariachiara Gabriele, Simonetta Cristina Di Simone and 3 more

Abstract readReview
In one paragraph

Review in Plants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Abdallah S Al-Sawa'eerNational Seeds Production Company, Amman 11183, Jordan.
Ali Al-SamydaiDepartment of Pharmaceutics and Pharmaceutical Technology, Pharmacological and Diagnostic Research Centre, Faculty of Pharmacy, Al-Ahliyya Amman University, Amman 19111, Jordan.ORCID 0000-0003-0093-2310
Lama OdehDepartment of Biology and Biotechnology, Faculty of Science, The Hashemite University, Zarqa 13133, Jordan.
Fatima Haj AhmadDepartment of Biotechnology, Faculty of Agricultural Technology, Al-Balqa Applied University, Al-Salt 19117, Jordan.ORCID 0000-0001-5347-3918
Renata ObekhDepartment of Biology and Biotechnology, Faculty of Science, The Hashemite University, Zarqa 13133, Jordan.
Yousef M Abd ElqaderNational Seeds Production Company, Amman 11183, Jordan.
Anas KhaleelDepartment of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmacy and Medical Sciences, University of Petra, Amman 11196, Jordan.ORCID 0000-0001-7584-2438
Ahmad M Al-AthamnehDepartment of Nutrition, Faculty of Pharmacy and Medical Sciences, University of Petra, Amman 11196, Jordan.ORCID 0000-0002-1387-1329
Mariachiara GabrieleBotanical Garden "Giardino dei Semplici", Department of Pharmacy, "G. d'Annunzio" University "Chieti-Pescara", Via dei Vestini n. 31, 66100 Chieti, Italy.ORCID 0009-0005-0774-2562
Simonetta Cristina Di SimoneBotanical Garden "Giardino dei Semplici", Department of Pharmacy, "G. d'Annunzio" University "Chieti-Pescara", Via dei Vestini n. 31, 66100 Chieti, Italy.ORCID 0000-0001-5041-3848
Claudio FerranteBotanical Garden "Giardino dei Semplici", Department of Pharmacy, "G. d'Annunzio" University "Chieti-Pescara", Via dei Vestini n. 31, 66100 Chieti, Italy.ORCID 0000-0001-9431-9407
Luigi MenghiniBotanical Garden "Giardino dei Semplici", Department of Pharmacy, "G. d'Annunzio" University "Chieti-Pescara", Via dei Vestini n. 31, 66100 Chieti, Italy.ORCID 0000-0002-7346-7395
Ahmed S A Ali AghaDepartment of Pharmaceutical Sciences, School of Pharmacy, The University of Jordan, Amman 11942, Jordan.ORCID 0009-0000-8516-2313

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Seed germination and early seedling development are critical determinants of crop establishment, stress tolerance, and yield stability, yet these stages remain insufficiently integrated into contemporary crop improvement strategies. Recent advances across genome editing, microbiome-assisted seed treatments, nanotechnology-enabled priming, and artificial intelligence-guided phenotyping have generated substantial but fragmented insights into early developmental regulation. This review synthesizes recent advances across early plant development research. It demonstrates that seemingly diverse technologies converge on a limited set of regulatory control nodes, including abscisic acid-gibberellin balance, redox homeostasis, and root system architectural plasticity. By integrating evidence from molecular, microbial, physicochemical, and computational studies, early plant ontogeny is presented as a tunable regulatory state governed by quantitative thresholds rather than as a strictly predetermined genetic process. Advances in deep learning, reinforcement learning, and high-throughput phenotyping further enable the modeling and optimization of early developmental trajectories across genotype by environment contexts. Together, these insights establish early development as a programmable target for crop improvement and provide a mechanistic foundation for designing integrated interventions that enhance developmental uniformity, stress resilience, and yield stability across diverse agroecological systems.

Indexed as

artificial intelligenceCRISPR-Casearly seedling vigormulti-omicsnanoprimingseed germination

Identifiers

PMID41829816
PMCPMC12987265

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.