Evidence map›Paper›PMID 41829729›Full record

ReviewPlants (Basel, Switzerland)2026

Primary Stress Factors and Adaptive Mechanisms of Microalgae in Space Environments and Their Applications in Space Life Support Systems.

Siyao Dai, Weiying Feng, Jeffrey Lae, Xuezheng Yu, Chia Min Ho, Fang Yang, Qingfeng Miao, Pengcheng Duan

Abstract readReview
In one paragraph

Review in Plants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Siyao DaiSchool of Materials Science and Engineering, Beihang University, Beijing 100191, China.
Weiying FengSchool of Materials Science and Engineering, Beihang University, Beijing 100191, China.ORCID 0000-0001-8478-1171
Jeffrey LaeJ L Algae Science LB, Macgregor, Brisbane, QLD 4109, Australia.ORCID 0009-0002-9190-6272
Xuezheng YuSchool of Materials Science and Engineering, Beihang University, Beijing 100191, China.
Chia Min HoSchool of Materials Science and Engineering, Beihang University, Beijing 100191, China.
Fang YangState Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Beijing 100012, China.ORCID 0000-0002-9861-8487
Qingfeng MiaoCollege of Water Conservancy and Civil Engineering, Inner Mongolia Agricultural University, Hohhot 010018, China.ORCID 0000-0002-2584-6833
Pengcheng DuanInner Mongolia Algal Life Science Co., Ltd., Ulanqab 011800, China.

Funding

Key Research and Development and Technology Transfer Program of Inner Mongolia Autonomous Region in China 2025YFHH0145National Natural Science Foundation of China 42177400Science and Technology Major Project of Ordos City in China ZD20232301
6 · The paper itself

Abstract

Cyanobacteria and eukaryotic microalgae (collectively referred to here as 'microalgae') represent early-evolving oxygenic phototrophs and are widely considered ideal candidates for bioregenerative life support systems (BLSS) due to their high metabolic efficiency and ecological robustness. Photosynthetic systems centered on microalgae show strong promise for life support in future deep-space exploration. However, the space environment imposes a range of harsh stressors, including intense radiation, extreme temperature fluctuations, vacuum conditions, and microgravity, all of which critically challenge biological survival. The capacity to resist extreme environments, maintain viability, and reproduce is of great significance. This review systematically summarizes the responses and adaptive mechanisms of microalgae in extraterrestrial settings, including the regulation of radiation defense, photosynthetic metabolic reprogramming, structural protection, and dormancy strategies. Furthermore, the practical applications of microalgae in BLSS encompass atmospheric regulation, food supplementation, and wastewater recycling. By highlighting both achievements and current limitations, this review provides insights into the potential of microalgae as a cornerstone for future long-duration space missions and planetary base construction, while identifying key directions for future research on strain improvement, photobioreactor optimization, and system integration.

Indexed as

deep space explorationmicroalgaespace environmentspace radiation

Identifiers

PMID41829729
PMCPMC12986780

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.