A Single-Cell Optically Pumped Intrinsic Gradiometer.

Optically pumped magnetometers (OPMs) provide a non-cryogenic alternative to superconducting quantum interference devices (SQUIDs) for detecting weak biomagnetic fields. We report the design, construction, and characterization of a single-cell intrinsic OPM gradiometer. The gradiometer employs a rubidium-87 vapor cell in an orthogonal pump and probe beam configuration. The pump beam was split to illuminate two parallel sensing regions of the cell, separated by a baseline of 3 cm, with opposing circular polarization. A linearly polarized probe beam propagated through both regions and was captured by a balanced polarimeter whose output directly measured the spatial magnetic gradient. This prototype achieved a common-mode rejection ratio exceeding 50 dB and a sensitivity of 267 pT/cm/√Hz without passive magnetic shielding, using active ambient-field coils. As a proof of concept, we recorded preliminary cardiac-synchronous magnetic measurements using an optical pulse sensor for beat segmentation. After bandpass filtering and ensemble averaging, a cardiac-synchronous waveform was observed, consistent with cardiac timing. Unlike many multi-cell gradiometers that require complex calibration, modulation, and passive shielding, this single-cell design reduces cost and complexity.