Evidence map›Paper›PMID 41829162›Full record

ArticleFoods (Basel, Switzerland)2026

Per- and Polyfluoroalkyl Substance Levels in Commercial and Home-Produced Eggs in Croatia.

Nina Bilandžić, Ines Varga, Jelena Kaurinović, Bruno Čalopek, Maja Đokić, Ivana Varenina, Božica Solomun Kolanović, Marija Sedak, Luka Cvetnić, Damir Pavliček and 1 more

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Nina BilandžićLaboratory for Residue Control, Department of Veterinary Public Health, Croatian Veterinary Institute, Savska Cesta 143, 10000 Zagreb, Croatia.ORCID 0000-0002-0009-5367
Ines VargaLaboratory for Residue Control, Department of Veterinary Public Health, Croatian Veterinary Institute, Savska Cesta 143, 10000 Zagreb, Croatia.ORCID 0000-0002-1089-9086
Jelena KaurinovićLaboratory for Residue Control, Department of Veterinary Public Health, Croatian Veterinary Institute, Savska Cesta 143, 10000 Zagreb, Croatia.ORCID 0009-0004-9891-1343
Bruno ČalopekLaboratory for Residue Control, Department of Veterinary Public Health, Croatian Veterinary Institute, Savska Cesta 143, 10000 Zagreb, Croatia.
Maja ĐokićLaboratory for Residue Control, Department of Veterinary Public Health, Croatian Veterinary Institute, Savska Cesta 143, 10000 Zagreb, Croatia.ORCID 0000-0002-3071-6208
Ivana VareninaLaboratory for Residue Control, Department of Veterinary Public Health, Croatian Veterinary Institute, Savska Cesta 143, 10000 Zagreb, Croatia.
Božica Solomun KolanovićLaboratory for Residue Control, Department of Veterinary Public Health, Croatian Veterinary Institute, Savska Cesta 143, 10000 Zagreb, Croatia.ORCID 0000-0002-4073-2498
Marija SedakLaboratory for Residue Control, Department of Veterinary Public Health, Croatian Veterinary Institute, Savska Cesta 143, 10000 Zagreb, Croatia.ORCID 0000-0001-6861-0436
Luka CvetnićLaboratory for Mastitis and Raw Milk Quality, Department of Bacteriology and Parasitology, Croatian Veterinary Institute, Savska 143, 10000 Zagreb, Croatia.ORCID 0009-0009-3474-6998
Damir PavličekLaboratory for Microbiology and Analytical Chemistry, Department Križevci, Croatian Veterinary Institute Zagreb, Zakmardijeva 10, 48260 Križevci, Croatia.ORCID 0000-0003-1772-6257
Elena FattoreCentre of Preclinical Toxicology and Biochemistry, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, 20156 Milano, Italy.ORCID 0000-0003-0556-2291

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to measure per- and polyfluoroalkyl substance (PFAS) levels in eggs collected in Croatia and to identify differences between commercially produced eggs (cage, barn, and organic) and home-produced eggs (HPE). Thirty PFAS compounds were analyzed using high-performance liquid chromatography coupled with high-resolution mass spectrometry. In HPE, the highest detection frequencies above the limit of quantification were observed for perfluorooctane sulfonic acid (PFOS) at 67.6%, perfluorononanoic acid (PFNA) at 43.2%, perfluoro-n-decanoic acid (PFDA) at 43.2%, and perfluoro-n-dodecanoic acid (PFDoDA) at 35.8%. Perfluorooctanoic acid (PFOA) was detected only in HPE. Furthermore, HPE exhibited significantly higher mean lower bound (LB) and upper bound (UB) levels for all measured compounds, as well as for the sum of the four main PFAS (∑4PFAS: PFOS, PFOA, PFNA, and perfluorohexane sulfonic acid [PFHxS]), with values of 0.263 and 0.44 µg/kg, respectively. Cage eggs showed the lowest LB and UB levels. The dietary contribution of ∑4PFAS to the established tolerable weekly intake (TWI) limit of 4.4 ng/kg bw indicated that children up to nine years old are the most vulnerable to exposure, particularly infants and toddlers consuming HPE. Significantly lower exposure was observed with cage eggs; therefore, consumers are advised to prefer these eggs.

Indexed as

Croatiaeggsfood contaminantsfood safetyPFASrisk assessment

Identifiers

PMID41829162
PMCPMC12984560

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.