Evidence map›Paper›PMID 41828983›Full record

ReviewAnimals : an open access journal from MDPI2026

Environmental and Physiological Regulation of Reproduction in the Goldfish: Gonadal Development, Maturation, and Spawning Behavior: A Review.

Makito Kobayashi, Eri Iwata, Peter W Sorensen

Abstract readReview
In one paragraph

Review in Animals : an open access journal from MDPI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Makito KobayashiField Studies Institute for Environmental Education, Tokyo Gakugei University, Koganei 184-8501, Tokyo, Japan.
Eri IwataFaculty of Veterinary Medicine, Okayama University of Science, Ikoino-oka, Imabari 794-8555, Ehime, Japan.
Peter W SorensenDepartment of Fisheries, Wildlife and Conservation Biology, University of Minnesota, 1980 Folwell Ave., St. Paul, MN 55108, USA.ORCID 0000-0003-0321-1279

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The goldfish, a member of the Cyprinidae (minnow family) is an important and relevant model for understanding how fish function and reproduce and can be better managed. Here, we review recent studies of this species and its strengths as a model system. First, we review current understanding of how its neuroendocrine system regulates gonadotropin release, and then steroidogenesis and finally gonadal maturation in both males and females. Endocrine determinants of gender and sexual plasticity are described. Effects of the fish androgen, 11-ketotestosterone, on sexual and spawning behavior of males and females are reviewed. We also describe how several hormones (androstenedione, 17,20β-dihydroxy-4-pregen-3-one, prostaglandin F2α) and their metabolites function as "hormonal pheromones" to synchronize male-female spawning behavior and physiology. Insight provided by the goldfish has enhanced understanding of the neurobiology, toxicology, and comparative physiology of other fishes and provided lessons applicable to the culture of commercial carp and the control of invasive species, as well as conservation.

Indexed as

GnRH gonadotropinsgoldfishinvasive speciesprostaglandinsex pheromonessex steroidssexual behaviorsexual plasticityspawning behavior

Identifiers

PMID41828983
PMCPMC12984928

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.