In Vitro Safety Profiling and Leukoderma-Relevant Hazard Assessment of Raspberry Ketone Versus

Manyi Hou, Xiaoyu Yang, Xin Nong, Congfen He, Yan Liang, Lei Liu

Abstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Manyi HouDepartment of Cosmetics, School of Light Industry Science and Engineering, Beijing Technology and Business University, Beijing 100048, China.

Xiaoyu YangDepartment of Cosmetics, School of Light Industry Science and Engineering, Beijing Technology and Business University, Beijing 100048, China.

Xin NongDepartment of Cosmetics, School of Light Industry Science and Engineering, Beijing Technology and Business University, Beijing 100048, China.

Congfen HeDepartment of Cosmetics, School of Light Industry Science and Engineering, Beijing Technology and Business University, Beijing 100048, China.

Yan LiangSchool of Kinesiology and Health, Capital University of Physical Education and Sports, No. 11 Beisanhuanxi Road, Beijing 100191, China.

Lei LiuDepartment of Cosmetics, School of Light Industry Science and Engineering, Beijing Technology and Business University, Beijing 100048, China.ORCID 0000-0003-3943-6381

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Safety concerns surrounding skin-lightening agents have intensified following chemical leukoderma linked to rhododendrol. Here, we performed an in vitro safety and hazard profiling comparison of raspberry ketone (RK) and a total anthraquinone fraction from

Indexed as

AnthraquinonesKeratinocytesMelanocytesAnimalsApoptosisCell LineCell SurvivalCoculture TechniquesHumansMiceReactive Oxygen SpeciesAnthraquinonesReactive Oxygen Specieschemical leukodermaER stressoxidative stressPolygonum cillinervepurine metabolismraspberry ketonetargeted metabolomicstotal anthraquinones

Identifiers

PMID41828812

DOI10.3390/molecules31050822

PMCPMC12985728

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.