Evidence map›Paper›PMID 41828788›Full record

ArticleMolecules (Basel, Switzerland)2026

Rapid Analysis of Phytic Acid by Paper Spray Mass Spectrometry.

Ping Guo, Sijie Zhu, Bo Chen

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ping GuoKey Laboratory of Phytochemical R&D of Hunan Province, Hunan Normal University, No. 36, Lushan Road, Changsha 410081, China.
Sijie ZhuKey Laboratory of Phytochemical R&D of Hunan Province, Hunan Normal University, No. 36, Lushan Road, Changsha 410081, China.
Bo ChenKey Laboratory of Phytochemical R&D of Hunan Province, Hunan Normal University, No. 36, Lushan Road, Changsha 410081, China.

Funding

National Sustainable Development Demonstration Zone Project (Chenzhou) 2022sfq49the National Natural Science Foundation of China 22276049
6 · The paper itself

Abstract

Phytic acid (PA), owing to its strong acidity and multidentate metal-chelating properties, readily forms multiple adduct/complex ions in mass spectrometry and is prone to pronounced matrix effects, resulting in complicated spectra and compromised sensitivity and quantitative robustness, which poses a major challenge for rapid and accurate PA quantification. Herein, we developed a rapid quantitative method for PA based on trimethylsilyldiazomethane (TMSD) methyl-ester derivatization coupled with paper spray mass spectrometry (PS-MS). PA was derivatized with TMSD to yield the methylated product (PA-Me), and the derivative solution was purified via "post-derivatization nitrogen blow-down followed by water reconstitution", thereby markedly reducing background interference. In positive-ion mode, the stable sodium adduct ion [PA-Me+Na]

Indexed as

Mass SpectrometryPaperPhytic AcidDiazomethaneLimit of DetectionOryzaTrimethylsilyl CompoundsDiazomethanePhytic AcidTrimethylsilyl Compoundstrimethylsilyldiazomethanederivatizationhigh-throughput analysispaper spray mass spectrometryphytic acidrice bran products

Identifiers

PMID41828788
PMCPMC12986130

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.