ArticleInternational journal of molecular sciences2026
Ultrasound-Regulated Molecular Reorganization and Property Enhancement in Gelatin-Glycerol Films.
Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
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2 authors.
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Abstract
The replacement of petroleum-based plastics with sustainable and biodegradable materials remains a critical challenge for food packaging and biomedical applications. Gelatin is an attractive natural biopolymer for film fabrication; however, its inherent brittleness, moisture sensitivity, and limited structural stability restrict practical use. In this work, for the first time, low-power direct-probe ultrasonication is introduced as a green and additive-free strategy to regulate molecular organization and enhance the performance of gelatin-glycerol composite films. Systematic variation in ultrasonic power and treatment duration revealed a strong dependence of film structure and properties on processing conditions. Low-power ultrasonication (20 W) promoted gelatin-glycerol interactions, induced a transition from loosely organized molecular arrangements to helix-like molecular packing at the nanometer scale, and produced smooth, compact microscale surface morphologies. As a result, these films exhibited enhanced hydrophilicity, reduced surface defects, and improved thermal stability. In contrast, high-power ultrasonication generated excessive cavitation, leading to large-scale porous structures and diminished thermal and surface performance. Therefore, this work identifies a distinct low-power ultrasonic window that enables controlled molecular reorganization and hierarchical structure formation in gelatin-glycerol systems. Structural and physicochemical analyses using SEM, FTIR, XRD, water contact angle measurements, and thermogravimetric analysis collectively elucidate the ultrasound-driven structure-property relationships within the gelatin-glycerol matrix. Overall, this study demonstrates that controlled ultrasonication enables precise tuning of gelatin-based film architecture and properties, offering a scalable and environmentally friendly route to high-performance biodegradable materials for sustainable packaging and biomedical applications.
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