Evidence map›Paper›PMID 41828638›Full record

ReviewInternational journal of molecular sciences2026

Gene Amplification in Rhabdomyosarcoma: Lessons from a Rare Cancer.

Frederic G Barr

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Frederic G BarrLaboratory of Pathology, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.ORCID 0000-0002-1051-7447

Funding

Studies of amplification in rhabdomyosarcomaZIABC011378 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI BARR, FREDERIC · 2011 to 2025
$7.2M
NCI NIH HHS ZIABC011378
6 · The paper itself

Abstract

Studies of the pediatric soft tissue cancer alveolar rhabdomyosarcoma have contributed to the current understanding of the diverse set of molecular changes that occur as part of the gene amplification process. In accord with the traditional view of amplification, the amplicon from the 2p24 chromosomal region primarily involves a single protein-coding gene (

Indexed as

Gene AmplificationRhabdomyosarcomaRhabdomyosarcoma, AlveolarAnimalsCyclin-Dependent Kinase 4HumansTranslocation, GeneticCyclin-Dependent Kinase 4alveolar rhabdomyosarcomaCDK4gene amplificationMIR17HGMYCNPAX3::FOXO1PAX7::FOXO1SHMT2

Identifiers

PMID41828638
PMCPMC12986286

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.