Evidence map›Paper›PMID 41828634›Full record

ArticleInternational journal of molecular sciences2026

Combining Yeast Display and Bacterial Genomic Library for the Unbiased Isolation of Novel Polysaccharide-Binding Peptides.

Angela Stabile, Gaia Scaramella, Simone Puccio, John Brady, Lise Goltermann, Tim Tolker-Nielsen, Barbara Bellich, Simone De Zotti, Cristina Lagatolla, Fortunato Ferrara and 3 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Angela StabileDepartment of Life Sciences, University of Trieste, Via L. Giorgieri 5, 34127 Trieste, Italy.ORCID 0009-0008-7748-9795
Gaia ScaramellaDepartment of Life Sciences, University of Trieste, Via L. Giorgieri 5, 34127 Trieste, Italy.ORCID 0009-0006-4689-2683
Simone PuccioLaboratory of Translational Immunology, Istituto di Ricovero e Cura a Carattere Scientifico Humanitas Research Hospital, Via Manzoni 56, 20089 Rozzano, Italy.ORCID 0000-0003-4007-4365
John BradyFood Science Department, Cornell University, 101A Stocking Hall, Ithaca, NY 14853, USA.ORCID 0000-0002-7791-0817
Lise GoltermannCosterton Biofilm Center, Department of Immunology and Microbiology, University of Copenhagen, Blegdamsvej 3B, DK-2200 Copenhagen, Denmark.ORCID 0000-0002-6679-9762
Tim Tolker-NielsenCosterton Biofilm Center, Department of Immunology and Microbiology, University of Copenhagen, Blegdamsvej 3B, DK-2200 Copenhagen, Denmark.
Barbara BellichInstitute for Maternal and Child Health, Istituto di Ricovero e Cura a Carattere Scientifico "Burlo Garofolo", Via dell'Istria 65/1, 34137 Trieste, Italy.ORCID 0000-0002-5257-6584
Simone De ZottiDepartment of Life Sciences, University of Trieste, Via L. Giorgieri 5, 34127 Trieste, Italy.
Cristina LagatollaDepartment of Life Sciences, University of Trieste, Via L. Giorgieri 5, 34127 Trieste, Italy.ORCID 0000-0001-5739-6761
Fortunato FerraraSpecifica Inc., an IQVIA Laboratories Company, Santa Fe, NM 87501, USA.
Roberto RizzoDepartment of Life Sciences, University of Trieste, Via L. Giorgieri 5, 34127 Trieste, Italy.ORCID 0000-0002-9809-592X
Paola CescuttiDepartment of Life Sciences, University of Trieste, Via L. Giorgieri 5, 34127 Trieste, Italy.ORCID 0000-0003-3744-2198
Daniele SblatteroDepartment of Life Sciences, University of Trieste, Via L. Giorgieri 5, 34127 Trieste, Italy.ORCID 0000-0003-4309-242X

Funding

Structural Investigations of Biofilm Matrices for Novel Antibiofilm StrategiesR01GM123283 · NIGMS · CORNELL UNIVERSITY · PI BRADY, JOHN W · 2017 to 2023
$1.7M
NIGMS NIH HHS R01 GM123283NIH Common Fund GM123283Novo Nordisk Foundation NNF22OC0080132
6 · The paper itself

Abstract

Here, we present a novel yeast surface display-based platform for the discovery of biofilm-associated exopolysaccharide-binding peptides. Unlike conventional synthetic libraries, our approach utilizes the genomic diversity of

Indexed as

BurkholderiaGenome, BacterialGenomic LibraryPeptidesPolysaccharidesSaccharomyces cerevisiaeBiofilmsCell Surface Display TechniquesPeptide LibraryProtein BindingPeptide LibraryPeptidesPolysaccharidesantibiofilm peptidesbiofilmpolysaccharidesyeast display

Identifiers

PMID41828634
PMCPMC12986056

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.