Evidence map›Paper›PMID 41828626›Full record

ArticleInternational journal of molecular sciences2026

C282Y Homozygosity Increases Erythrocyte Turnover and Decreases HbA1c-A Population-Based Study.

Rebekka Hillingsø, Alisa Devedzic Kjaergaard, Morten Kranker Larsen, Thomas Mandrup-Poulsen, Henrik Enghusen Poulsen, Mathis Mottelson, Jesper Brix Petersen, Børge Grønne Nordestgaard, Hans Carl Hasselbalch, Stig Egil Bojesen and 3 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Rebekka HillingsøFaculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.
Alisa Devedzic KjaergaardDepartment of Psychiatry, Horsens Hospital, 8700 Horsens, Denmark.
Morten Kranker LarsenDepartment of Hematology, Zealand University Hospital, 4000 Roskilde, Denmark.
Thomas Mandrup-PoulsenDepartment of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.ORCID 0000-0002-3215-9273
Henrik Enghusen PoulsenDepartment of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.ORCID 0000-0003-4242-9924
Mathis MottelsonDepartment of Hematology, Zealand University Hospital, 4000 Roskilde, Denmark.ORCID 0000-0001-8736-2618
Jesper Brix PetersenDepartment of Hematology, Danish Red Blood Cell Center, Rigshospitalet, 2100 Copenhagen, Denmark.
Børge Grønne NordestgaardDepartment of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.
Hans Carl HasselbalchDepartment of Hematology, Zealand University Hospital, 4000 Roskilde, Denmark.
Stig Egil BojesenDepartment of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.
Jens HelbyDepartment of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.ORCID 0000-0002-1876-8187
Andreas GlenthøjDepartment of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.ORCID 0000-0003-2082-0738
Christina EllervikDepartment of Laboratory Medicine, Boston Children's Hospital, Boston, MA 02115, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Individuals with C282Y/C282Y in the hemochromatosis

Indexed as

ErythrocytesGlycated HemoglobinHemochromatosisHemochromatosis ProteinHomozygoteAdultAgedDenmarkErythrocyte IndicesFemaleGenotypeHumansMaleMiddle AgedOxidative StressGlycated HemoglobinHemochromatosis Proteinhemoglobin A1c protein, humanHFE protein, humanC282Y/C282Yerythrocyteserythrocyte survivalerythrocyte turnoverHbA1cHFEMCHCMCVoxidative stressred blood cellsreticulocytestransferrin saturation

Identifiers

PMID41828626
PMCPMC12986277

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.