Evidence map›Paper›PMID 41828623›Full record

ArticleInternational journal of molecular sciences2026

Evaluation of an ESAT-6 Recombinant Skin Test Reagent for Bovine Tuberculosis Diagnosis in Guinea Pigs and Cattle.

Matías Iván Gatto, Sol Ferrero, Florencia Tonini, Marcela Desio, Gerardo Rodríguez, Fernando Martino, Bernardo Alonso, Claudio Paolazzi, Claudia Argüelles, Gustavo Helguera

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Matías Iván GattoPharmaceutical Biotechnology Laboratory, Institute of Biology and Experimental Medicine (IBYME-CONICET), Ciudad Autónoma de Buenos Aires C1428BFA, Argentina.
Sol FerreroPharmaceutical Biotechnology Laboratory, Institute of Biology and Experimental Medicine (IBYME-CONICET), Ciudad Autónoma de Buenos Aires C1428BFA, Argentina.
Florencia ToniniA.V.I.S. Veterinary Practice, Suardi, Santa Fe S2349, Argentina.
Marcela DesioNational Administration of Laboratories and Health Institutes "Dr. Carlos Malbrán" (ANLIS), National Institute of Biological Production (INPB), Department of Diagnostic Reagents, Mycobacterial Derivatives Service, Ciudad Autónoma de Buenos Aires C1281AEF, Argentina.ORCID 0009-0009-7550-6878
Gerardo RodríguezNational Administration of Laboratories and Health Institutes "Dr. Carlos Malbrán" (ANLIS), National Institute of Biological Production (INPB), Department of Diagnostic Reagents, Mycobacterial Derivatives Service, Ciudad Autónoma de Buenos Aires C1281AEF, Argentina.
Fernando MartinoA.V.I.S. Veterinary Practice, Suardi, Santa Fe S2349, Argentina.
Bernardo AlonsoNational Food Safety and Quality Service (SENASA), General Directorate of Laboratory and Technical Control (DILAB-SENASA), Martínez, Buenos Aires C1063ACD, Argentina.
Claudio PaolazziAgropharma Salud Animal S.A., Moreno, Buenos Aires B1744JFN, Argentina.
Claudia ArgüellesNational Administration of Laboratories and Health Institutes "Dr. Carlos Malbrán" (ANLIS), National Institute of Biological Production (INPB), Department of Diagnostic Reagents, Mycobacterial Derivatives Service, Ciudad Autónoma de Buenos Aires C1281AEF, Argentina.
Gustavo HelgueraPharmaceutical Biotechnology Laboratory, Institute of Biology and Experimental Medicine (IBYME-CONICET), Ciudad Autónoma de Buenos Aires C1428BFA, Argentina.ORCID 0000-0003-1509-3564

Funding

Agencia Nacional de Promoción Científica y Tecnológica, Argentina FONCYT PICT 2018 3954Agencia Nacional de Promoción Científica y Tecnológica, Argentina FONCYT PID 2015 0034Agencia Nacional de Promoción de la Investigación, el Desarrollo Tecnológico y la Innovación FONCYT IP-COVID 19 - 929Fundación Bigand, Argentina N/AFundación René Barón, Argentina N/AFundación Williams N/AInstituto Nacional del Cáncer INC 2018 2020
6 · The paper itself

Abstract

Bovine purified protein derivative (PPD-B), a crude protein extract from

Indexed as

Antigens, BacterialBacterial ProteinsSkin TestsTuberculin TestTuberculosis, BovineAnimalsCattleGuinea PigsHypersensitivity, DelayedMycobacterium bovisRecombinant Fusion ProteinsRecombinant ProteinsTuberculinAntigens, BacterialBacterial ProteinsESAT-6 protein, Mycobacterium tuberculosisRecombinant Fusion ProteinsRecombinant ProteinsTuberculinbovine tuberculosisdelayed-type hypersensitivityESAT-6recombinant antigenskin test

Identifiers

PMID41828623
PMCPMC12986123

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.