Evidence map›Paper›PMID 41828606›Full record

ArticleInternational journal of molecular sciences2026

Age-Associated Metabolomic Changes in Human Spermatozoa.

Mohd Amin Beg, Md Shawkat Khan, Ishfaq Ahmad Sheikh, Taha Abo-Almagd Abdel-Meguid Hamoda, Mohammad Imran Khan, Priyanka Sharma, Ali Hasan Alkhzaim, Kenaz Basem Abuzenada, Arif Mohammed, Abrar Ahmad and 2 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mohd Amin BegKing Fahd Medical Research Center, King Abdulaziz University, Jeddah 21589, Saudi Arabia.ORCID 0000-0002-8495-4738
Md Shawkat KhanKing Fahd Medical Research Center, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Ishfaq Ahmad SheikhKing Fahd Medical Research Center, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Taha Abo-Almagd Abdel-Meguid HamodaDepartment of Urology, Faculty of Medicine, King Abdulaziz University Hospital, Jeddah 21589, Saudi Arabia.ORCID 0000-0002-8070-4088
Mohammad Imran KhanResearch Center, King Faisal Specialist Hospital & Research Center, Jeddah 21499, Saudi Arabia.
Priyanka SharmaCenter of Innovation in Personalized Medicine, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Ali Hasan AlkhzaimDepartment of Urology, Faculty of Medicine, King Abdulaziz University Hospital, Jeddah 21589, Saudi Arabia.
Kenaz Basem AbuzenadaCenter of Innovation in Personalized Medicine, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Arif MohammedDepartment of Biological Sciences, College of Science, University of Jeddah, Jeddah 23890, Saudi Arabia.
Abrar AhmadDepartment of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah 21589, Saudi Arabia.ORCID 0000-0001-9439-7712
Adel Mohammad AbuzenadahKing Fahd Medical Research Center, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Erdogan MemiliCooperative Agricultural Research Center, College of Agriculture and Human Sciences, Prairie View A&M University, Prairie View, TX 77446, USA.

Funding

Ministry of Education in Saudi Arabia 1132
6 · The paper itself

Abstract

The functional genomic mechanisms contributing to aging-associated decline in fertility in men remain insufficiently elucidated. This study investigated age-related alterations in the sperm metabolome of healthy fertile Arab men across three groups: young adult (21-30 years,

Indexed as

AgingMetabolomeMetabolomicsSpermatozoaAdultBiomarkersChromatography, LiquidHumansMaleMiddle AgedTandem Mass SpectrometryYoung AdultBiomarkersaginghumanLC-MS/MSmetabolomicsspermatozoa

Identifiers

PMID41828606
PMCPMC12986010

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.