Evidence map›Paper›PMID 41828597›Full record

ArticleInternational journal of molecular sciences2026

Covalently Surface-Functionalized Porphyrins on Silica Nanoparticles for Efficient Photodynamic Therapy.

Daniel S Cavaco, Maria João Álvaro-Martins, Mafalda Domingues, Tiago Palmeira, Sandra N Pinto, Leandro M O Lourenço, Gil Gonçalves, Carla I M Santos, Ermelinda M S Maçôas

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Daniel S CavacoCentro de Química Estrutural, Institute of Molecular Sciences, and Departamento de Engenharia Química, Instituto Superior Técnico, Universidade de Lisboa, 1049-001 Lisboa, Portugal.ORCID 0000-0002-2381-4694
Maria João Álvaro-MartinsCentro de Química Estrutural, Institute of Molecular Sciences, and Departamento de Engenharia Química, Instituto Superior Técnico, Universidade de Lisboa, 1049-001 Lisboa, Portugal.
Mafalda DominguesiBB-Institute for Bioengineering and Biosciences, and Associate Laboratory i4HB-Institute for Health and Bioeconomy, and DBE-Department of Bioengineering, Instituto Superior Técnico, Universidade de Lisboa, 1049-001 Lisboa, Portugal.
Tiago PalmeiraCentro de Química Estrutural, Institute of Molecular Sciences, and Departamento de Engenharia Química, Instituto Superior Técnico, Universidade de Lisboa, 1049-001 Lisboa, Portugal.
Sandra N PintoiBB-Institute for Bioengineering and Biosciences, and Associate Laboratory i4HB-Institute for Health and Bioeconomy, and DBE-Department of Bioengineering, Instituto Superior Técnico, Universidade de Lisboa, 1049-001 Lisboa, Portugal.ORCID 0000-0002-3205-9459
Leandro M O LourençoLAQV-REQUIMTE, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0003-1624-6825
Gil GonçalvesCentre for Mechanical Technology and Automation (TEMA), University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0002-2302-9661
Carla I M SantosCentro de Química Estrutural, Institute of Molecular Sciences, and Departamento de Engenharia Química, Instituto Superior Técnico, Universidade de Lisboa, 1049-001 Lisboa, Portugal.
Ermelinda M S MaçôasCentro de Química Estrutural, Institute of Molecular Sciences, and Departamento de Engenharia Química, Instituto Superior Técnico, Universidade de Lisboa, 1049-001 Lisboa, Portugal.ORCID 0000-0001-8506-7025

Funding

Fundação para a Ciência e Tecnologia 2023.08400.CEECIND, DOI: 10.54499/2023.08400.CEECIND/CP2830/CT0013)
6 · The paper itself

Abstract

Silica nanoparticles (SiNPs) are widely explored as biocompatible platforms for the delivery of photosensitizers in photodynamic therapy (PDT). In this work, porphyrins bearing amine (PNH

Indexed as

NanoparticlesPhotochemotherapyPhotosensitizing AgentsPorphyrinsSilicon DioxideCell SurvivalHumansSinglet OxygenSpectroscopy, Fourier Transform InfraredPhotosensitizing AgentsPorphyrinsSilicon DioxideSinglet Oxygencancer therapynanohybridsphotodynamic therapyporphyrinssilica nanoparticles

Identifiers

PMID41828597
PMCPMC12986489

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.