Evidence map›Paper›PMID 41828531›Full record

ArticleInternational journal of molecular sciences2026

Tricyclic Pyrrole-Based Compounds as Zika Virus Inhibitors.

Gabriele Murineddu, Erika Plicanti, Paola Corona, Carlo Di Marzo, Battistina Asproni, Ilenia Lupinu, Giulia Lottini, Sandra Piras, Antonio Carta

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Special Issue "Antiviral Drugs Discovery".International journal of molecular sciences · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gabriele MurinedduDepartment of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0002-2791-9178
Erika PlicantiCentro Retrovirus, Department of Translational Research, University of Pisa, 56127 Pisa, Italy.ORCID 0000-0002-5488-605X
Paola CoronaDepartment of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0002-9182-478X
Carlo Di MarzoCentro Retrovirus, Department of Translational Research, University of Pisa, 56127 Pisa, Italy.
Battistina AsproniDepartment of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0002-0988-1882
Ilenia LupinuDepartment of Chemical, Physical, Mathematical and Natural Sciences, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0002-9457-7737
Giulia LottiniCentro Retrovirus, Department of Translational Research, University of Pisa, 56127 Pisa, Italy.ORCID 0000-0001-7902-9495
Sandra PirasDepartment of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.
Antonio CartaDepartment of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A small library of 23 pyrrole-based tricyclic derivatives bearing bulky amine moieties was synthesized, and all were evaluated for their antiviral activities against ZIKV and SARS-CoV. Three compounds, derivatives

Indexed as

Antiviral AgentsPyrrolesZika VirusAnimalsHumansAntiviral AgentsPyrrolesantiviral activitysynthesis of tricyclic pyrrolesWestern blot analysis

Identifiers

PMID41828531
PMCPMC12984852

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.