Evidence map›Paper›PMID 41828502›Full record

ArticleInternational journal of molecular sciences2026

Integrative Analysis on the Urinary Proteome of Diabetic Kidney Disease, with an Emphasis on Extracellular Matrix Proteins.

Sonnal Lohia, Jerome Zoidakis, Antonia Vlahou, Aggeliki Tserga

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sonnal LohiaCenter of Systems Biology, Biomedical Research Foundation of the Academy of Athens, 11527 Athens, Greece.
Jerome ZoidakisCenter of Systems Biology, Biomedical Research Foundation of the Academy of Athens, 11527 Athens, Greece.ORCID 0000-0002-4557-3430
Antonia VlahouCenter of Systems Biology, Biomedical Research Foundation of the Academy of Athens, 11527 Athens, Greece.ORCID 0000-0003-3284-5713
Aggeliki TsergaCenter of Systems Biology, Biomedical Research Foundation of the Academy of Athens, 11527 Athens, Greece.ORCID 0000-0002-5531-2111

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One of the key pathological features of Diabetic Kidney Disease (DKD) progression is the accumulation of extracellular matrix (ECM) proteins in kidneys, leading to thickening of the glomerular and tubular basement membranes, subsequently resulting in mesangial expansion, sclerosis, and tubulointerstitial fibrosis. Given the high prevalence of DKD among both T2DM and T1DM patients, as well as the complexity of its underlying molecular mechanisms, this study provides a comparative analysis of published urinary proteomics datasets in DKD (

Indexed as

Diabetic NephropathiesExtracellular Matrix ProteinsProteomeBiomarkersExtracellular MatrixGene Expression ProfilingHumansProteomicsBiomarkersExtracellular Matrix ProteinsProteomebiomarkersDKDECM proteinsextra-cellular matrixmatrisomeproteinsproteomicstranscriptomicsurine

Identifiers

PMID41828502
PMCPMC12985236

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.