Evidence map›Paper›PMID 41828352›Full record

ArticleInternational journal of molecular sciences2026

CQD: A Rapid and Accurate Tool for Identifying High-Confidence QTLs and Candidate Genes from GWAS Summary Statistics.

Xiangjian Gou, Shaohong Fu, Jiakun Li, Wanzhuo Gong, Qiaobo Wu, Yun Li, Jin Yang, Qiong Zou, Qin Yu, Lanrong Tao and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xiangjian GouHubei Hongshan Laboratory, Huazhong Agricultural University, Wuhan 430070, China.
Shaohong FuChengdu Academy of Agricultural and Forestry Sciences, Chengdu 611130, China.ORCID 0000-0002-9295-6506
Jiakun LiTriticeae Research Institute, Sichuan Agricultural University, Chengdu 611130, China.
Wanzhuo GongChengdu Academy of Agricultural and Forestry Sciences, Chengdu 611130, China.
Qiaobo WuChengdu Academy of Agricultural and Forestry Sciences, Chengdu 611130, China.
Yun LiChengdu Academy of Agricultural and Forestry Sciences, Chengdu 611130, China.
Jin YangChengdu Academy of Agricultural and Forestry Sciences, Chengdu 611130, China.
Qiong ZouChengdu Academy of Agricultural and Forestry Sciences, Chengdu 611130, China.
Qin YuChengdu Academy of Agricultural and Forestry Sciences, Chengdu 611130, China.
Lanrong TaoChengdu Academy of Agricultural and Forestry Sciences, Chengdu 611130, China.
Haoran ShiChengdu Academy of Agricultural and Forestry Sciences, Chengdu 611130, China.

Funding

Major Science and Technology Program in Chengdu 2024-YF09-00036-SNSichuan Innovation Team Program SCCXTD-2026-3
6 · The paper itself

Abstract

Genome-wide association studies (GWAS) are a powerful approach for elucidating the genetic architecture of complex traits. The widespread application of GWAS across diverse crop species has generated vast amounts of GWAS summary statistics, creating a pressing need for effective tools to identify high-confidence quantitative trait loci (QTLs) from these data. Here, we present Candidate QTL Detector (CQD), a tool that enables the rapid and accurate identification of confident QTL regions from GWAS summary statistics. To evaluate the performance of CQD, we reanalyzed 64 phenotypic traits from a previously published maize diversity panel. CQD identified 108 high-confidence QTLs from 4179 significant GWAS signals, and these QTLs harbored several well-characterized genes, including

Indexed as

Genome-Wide Association StudyQuantitative Trait LociZea maysPhenotypePolymorphism, Single NucleotideCQDfunctional genomicsGWAS summary statisticsQTL

Identifiers

PMID41828352
PMCPMC12984276

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.