In one paragraphArticle in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
12 authors.
Victoria ChaoulDepartment of Biochemistry and Molecular Genetics, American University of Beirut Medical Center, Riad El Solh, Beirut 1107 2020, Lebanon.ORCID 0009-0007-7583-8579 Omar ShmouryDepartment of Biochemistry and Molecular Genetics, American University of Beirut Medical Center, Riad El Solh, Beirut 1107 2020, Lebanon.ORCID 0009-0009-1945-5383 Ramy AlamDepartment of Biochemistry and Molecular Genetics, American University of Beirut Medical Center, Riad El Solh, Beirut 1107 2020, Lebanon.ORCID 0009-0003-0628-3291 Sara SaabDepartment of Biochemistry and Molecular Genetics, American University of Beirut Medical Center, Riad El Solh, Beirut 1107 2020, Lebanon.
Joelle MakoukjiDepartment of Biochemistry and Molecular Genetics, American University of Beirut Medical Center, Riad El Solh, Beirut 1107 2020, Lebanon.
Lynn Al AridiDepartment of Biochemistry and Molecular Genetics, American University of Beirut Medical Center, Riad El Solh, Beirut 1107 2020, Lebanon.ORCID 0009-0000-6053-8425 Nadine J MakhoulDepartment of Biochemistry and Molecular Genetics, American University of Beirut Medical Center, Riad El Solh, Beirut 1107 2020, Lebanon.ORCID 0009-0006-6870-2262 Jihane SoueidDepartment of Anatomy, Cell Biology and Physiological Sciences, American University of Beirut, Beirut 1107 2020, Lebanon.ORCID 0000-0002-1973-8705 Angelica V CarmonaFred and Pamela Buffett Cancer Center, UNMC Center for Drug Discovery, Department of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, NE 68105, USA.ORCID 0000-0001-9722-5254 Princess SimeonFred and Pamela Buffett Cancer Center, UNMC Center for Drug Discovery, Department of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, NE 68105, USA.ORCID 0009-0009-1220-7870 Paul C TrippierFred and Pamela Buffett Cancer Center, UNMC Center for Drug Discovery, Department of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, NE 68105, USA.ORCID 0000-0002-4947-5782 Rose-Mary BoustanyDepartment of Biochemistry and Molecular Genetics, American University of Beirut Medical Center, Riad El Solh, Beirut 1107 2020, Lebanon.ORCID 0000-0002-2066-0079 Funding
AUB Openminds fund # 610920NIH HHS NIH/HD R01HD106590NIH HHS NIH/MH R01MH127323
6 · The paper itselfAbstract
Neuronal ceroid lipofuscinosis type 6 (CLN6) is a fatal, autosomal recessive neurodegenerative disorder characterized by cognitive/motor impairment, vision loss, as well as neuronal loss and gliosis in the brain, and premature death. Onset typically occurs in childhood. No approved pharmacological treatments exist that halt or reverse disease progression. A novel flupirtine benzyl carbamate was orally administered to male and female
Indexed as
AminopyridinesCarbamatesNeuronal Ceroid-LipofuscinosesAnimalsBrainDisease Models, AnimalFemaleMaleMiceAminopyridinesCarbamatesflupirtineapoptosisbehavioral phenotypeCln6nclf mouse modelflupirtine benzyl carbamategliosisneuronal ceroid lipofuscinosis type 6 (CLN6 disease)
Identifiers
PMID41827875
PMCPMC12984176
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