Evidence map›Paper›PMID 41827861›Full record

ArticleCells2026

Deletion of TRPA1 Ion Channel Modulates the Central Stress Responses in a Mouse Model of Posttraumatic Stress Disorder.

János Konkoly, Laura Mária Szegner, Tünde Biró-Sütő, Eszter Luspay, Prabhat Kumar, Erika Kvak, Balázs Gaszner, Gergely Berta, Erika Pintér, Dóra Zelena and 1 more

Abstract read
In one paragraph

Article in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

János KonkolyDepartment of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, H-7624 Pécs, Hungary.
Laura Mária SzegnerDepartment of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, H-7624 Pécs, Hungary.
Tünde Biró-SütőDepartment of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, H-7624 Pécs, Hungary.
Eszter LuspayDepartment of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, H-7624 Pécs, Hungary.
Prabhat KumarInstitute of Physiology, Medical School, University of Pécs, H-7624 Pécs, Hungary.ORCID 0000-0002-2109-8591
Erika KvakInstitute of Physiology, Medical School, University of Pécs, H-7624 Pécs, Hungary.
Balázs GasznerDepartment of Anatomy, Medical School, University of Pécs, H-7624 Pécs, Hungary.ORCID 0000-0003-2830-2732
Gergely BertaDepartment of Medical Biology, Medical School, University of Pécs, H-7624 Pécs, Hungary.
Erika PintérDepartment of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, H-7624 Pécs, Hungary.ORCID 0000-0001-9898-632X
Dóra ZelenaInstitute of Physiology, Medical School, University of Pécs, H-7624 Pécs, Hungary.ORCID 0000-0001-5616-1100
Viktória KormosDepartment of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, H-7624 Pécs, Hungary.ORCID 0000-0002-3360-2425

Funding

Hungarian Academy of Sciences National Brain Research Program (NAP 3.0)National Research Development and Innovation Office of Hungary K141934 and K138763NKFI NKFI-146117Thematic Excellence Program 2021 Health Sub-program of the Ministry for Innovation and Technology in Hungary, within the framework of the EGA-16 project of Pécs University TKP2021-EGA-16University of Pécs Medical School 008_2025_PTE_RK/36University of Pécs Medical School KA-2024-12
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene DeletionStress Disorders, Post-TraumaticStress, PsychologicalTRPA1 Cation ChannelAnimalsClonidineCorticosteroneDisease Models, AnimalLocus CoeruleusMaleMiceMice, Inbred C57BLMice, KnockoutParaventricular Hypothalamic NucleusTyrosine 3-MonooxygenaseClonidineCorticosteroneTRPA1 Cation ChannelTrpa1 protein, mouseTyrosine 3-Monooxygenaseclonidineconditioned fearfoot shocklocus coeruleus (LC)paraventricular nucleus of the hypothalamus (PVN)posttraumatic stress disorder (PTSD)stress adaptationTRPA1

Identifiers

PMID41827861
PMCPMC12984887

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.